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Nanobody Based Imaging and Targeting of ECM in Disease and Development

Exclusively Licensed Technology / Case number: #19830HWJQ
Richard Hynes / Yushu Xie / Noor Jailkhani / Hidde Ploegh
Technology Areas: Biotechnology / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living

Vaccine Formulation Containing Dynamically Stabilized Immunostimulatory Oligonucleotide Micelles

Exclusively Licensed Technology / Case number: #15453H
Darrell J Irvine / Haipeng Liu
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living

Novel Memory-like NK Cell Based Chimeric Antigen Receptor (CAR) Targeting Mutated NPM1 in Myeloid Malignancies

Exclusively Licensed Technology / Case number: #22960J
Jianzhu Chen / James Ham / Han Dong / Jerome Ritz / Rizwan Romee / Guozhu Xie
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

SYNTHETIC HEPARIN MIMETICS AND USES THEREOF

Exclusively Licensed Technology / Case number: #22634HJQ
Christopher Chen / Jeroen Eyckmans / Jinling Yang / Linqing Li / Sangeeta Bhatia
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living

Versatile High Affinity Antibody to DOTA Chelates of Multiple Radionuclides

Exclusively Licensed Technology / Case number: #13506
Karl Dane Wittrup / Kelly Davis
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Alum Binding Proteins

Exclusively Licensed Technology, Tangible Property / Case number: #21571H
Darrell J Irvine / Yash Agarwal / Tyson Moyer / Karl Dane Wittrup
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living

A Booster Vaccine for CAR-T Cells

Exclusively Licensed Technology / Case number: #19933H
Darrell J Irvine / Leyuan Ma
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living

Specific Viral Targeting of Hematopoietic Stem Cells via Engineering of Viral Tropism

Exclusively Licensed Technology / Case number: #22988JQ
Michael Birnbaum / Cassandra Burnett / Kole Roybal / Stephanie Gaglione / Connor Dobson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living

Tumor-Specific CAR-T Cell Therapy for Treating Acute Myeloid Leukemia

Exclusively Licensed Technology / Case number: #21827
Jianzhu Chen / Guozhu Xie
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Combined Inhibition of Polo-like kinase 1 (Plk1) and Microtubule Polymerization for the Treatment of Cancer

Exclusively Licensed Technology / Case number: #21961
Michael Yaffe / Jesse C Patterson / Brian A Joughin
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

METHODS FOR IDENTIFYING CHIMERIC ANTIGEN RECEPTOR-TARGETING LIGANDS AND USES THEREOF

Exclusively Licensed Technology / Case number: #22227H
Darrell J Irvine / Benjamin Cossette / Leyuan Ma / Naveen Mehta / Karl Dane Wittrup
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

RNA-based Logic Circuits with RNA Binding Proteins, Aptamers and Small Molecules

Exclusively Licensed Technology / Case number: #16631HJ
Darrell J Irvine / Kei Endo / Hirohide Saito / Tyler Wagner / Jacob Becraft / Katie Bodner / Tasuku Kitada / Velia Siciliano / Maria Hottelet Foley / Liliana Wroblewska / Ron Weiss
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Enhancement of Peptide Antigenicity for T Cell Priming Using Albumin Binding Peptides

Exclusively Licensed Technology / Case number: #19388H
Darrell J Irvine / Rebecca Holden / Kelly Moynihan / Bradley L. Pentelute
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Probing and Manipulating Cell Functions Through Intracellular Delivery

Exclusively Licensed Technology / Case number: #17162HJ
Robert Langer / Sophia Liu / Megan Heimann / George Hartoularos / Shirley Mao / Gregory Szeto / Armon Sharei / Ulrich Von Andrian / Pamela Basto / Siddharth Jhunjhunwala / Darrell J Irvine / Klavs F. Jensen
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Antibody Brush Prodrug Conjugates

Exclusively Licensed Technology / Case number: #23260
Jeremiah A. Johnson / Samantha Kristufek / Yutong Dai / Landon Kilgallon / Valerie Lensch / Bin Liu / Wencong Wang / Peyton Shieh / Hung Nguyen
Technology Areas: Therapeutics
Impact Areas: Healthy Living

Gamma Entrainment Binds Higher Order Brain Regions, Improves Cognitive Function, and offers Neuroprotection

Exclusively Licensed Technology / Case number: #20070P
Li-Huei Tsai / Chinnakkaruppan Adaikkan
Technology Areas: Therapeutics
Impact Areas: Healthy Living

Methods and Compositions for Ameliorating or Inhibiting Decline in Memory or Intelligence or Improving Same

Exclusively Licensed Technology / Case number: #12090Q
Richard Wurtman / Lisa Teather / Judith Wurtman
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living

A Fully Synthetic Nanoparticle Vaccine Platform Technology Composed of Dendrimer-Based Lipidoid Nanomaterials, Self-Amplifying Ribose Nucleic Acids and Polyethylene Glycol

Exclusively Licensed Technology / Case number: #17873WJH
Robert Langer / David Canner / Jasdave Chahal / Omar Khan / Daniel Anderson / Hidde Ploegh / Tyler Jacks
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living

Rapid Solid Phase Peptide Synthesizer

Exclusively Licensed Technology / Case number: #15911
Klavs F. Jensen / Mark Simon / Bradley L. Pentelute / Patrick Heider / Andrea Adamo
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Delivery Device to Release Drug to Seminal Vesicle, the Prostate Gland, and the Ejaculatory Duct

Exclusively Licensed Technology / Case number: #12805J
Michael Cima / Irene Khalek / Heejin Lee / Jordan Dimitrakov
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

filtered: 70 results

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