Alum Binding Proteins

Exclusively Licensed

The present disclosure provides immunomodulatory fusion proteins-metal hydroxide complexes comprising an immunomodulatory domain adsorbed to a metal hydroxide via ligand exchange. The disclosure also features compositions and methods of using the same, for example, to treat cancer.

Researchers

Darrell J Irvine / Yash Agarwal / Tyson Moyer / Karl Dane Wittrup

Departments: David H Koch Institute for Integrative Cancer Res, Department of Chemical Engineering
Technology Areas: Chemicals & Materials: Metals, Nanotechnology & Nanomaterials / Therapeutics: Cell Based Therapy, Proteins & Antibodies
Impact Areas: Healthy Living

  • immunomodulatory fusion protein-metal hydroxide complexes and methods thereof
    United States of America | Published application
  • immunomodulatory fusion protein-metal hydroxide complexes and methods thereof
    United States of America | Granted | 11,642,409
  • immunomodulatory fusion protein-metal hydroxide complexes and methods thereof
    Japan | Published application
  • immunomodulatory fusion protein-metal hydroxide complexes and methods thereof
    Japan | Published application
  • immunomodulatory fusion protein-metal hydroxide complexes and methods thereof
    European Patent Convention | Published application

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