Probing and Manipulating Cell Functions Through Intracellular Delivery
Exclusively Licensed
Invention type: Technology
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Case number: #17162HJ
A method and device for preferentially delivering a compound such as an antigen to the cytosol of an immune cell. The method comprises passing a cell suspension comprising the target immune cell through a microfluidic device and contacting the suspension with the compound(s) or payload to be delivered.
Researchers
Robert Langer
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Sophia Liu
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Megan Heimann
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George Hartoularos
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Shirley Mao
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Gregory Szeto
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Armon Sharei
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Ulrich Von Andrian
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Pamela Basto
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Siddharth Jhunjhunwala
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Darrell J Irvine
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Klavs F. Jensen
Departments: Office of the Institute Professors, Department of Chemical Engineering
Technology Areas: Biotechnology: Biomedical Devices & Systems / Drug Discovery and Research Tools: Cell Interrogation / Therapeutics: Nucleic Acids, Proteins & Antibodies, Small Molecules
Impact Areas: Healthy Living
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delivery of biomolecules to immune cells
United States of America | Published application -
delivery of biomolecules to immune cells
Singapore | Granted | 11,201,703,044 -
delivery of biomolecules to immune cells
Japan | Granted | 7,523,203 -
delivery of biomolecules to immune cells
European Patent Convention | Published application -
delivery of biomolecules to immune cells
Canada | Published application -
delivery of biomolecules to immune cells
United States of America | Granted | 11,111,472 -
delivery of biomolecules to immune cells
Russian Federation | Granted | 2,739,794 -
delivery of biomolecules to immune cells
Israel | Granted | 252,005 -
delivery of biomolecules to immune cells
China | Published application -
delivery of biomolecules to immune cells
Korea (south) | Published application -
delivery of biomolecules to immune cells
Korea (south) | Published application -
delivery of biomolecules to immune cells
Japan | Published application -
delivery of biomolecules to immune cells
Australia | Granted | 2,022,201,222
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