Antibody Brush Prodrug Conjugates
Exclusively Licensed
Invention type: Technology
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Case number: #23260Q
The present disclosure provides enynes, end-functionalized polymers, conjugates, methods of preparation, compositions, kits, and methods of use. The conjugates comprise at least (1) a peptide (e.g., an antibody), protein, nucleoprotein, mucoprotein, lipoprotein, glycoprotein, or polynucleotide; and (2) a polymer comprising a pharmaceutical agent. The conjugates may be useful in delivering (e.g., targeted delivering) the pharmaceutical agent to a subject in need thereof or cell or treating, preventing, or diagnosing a disease.
Researchers
Jeremiah A. Johnson
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Samantha Kristufek
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Yutong Dai
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Landon Kilgallon
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Valerie Lensch
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Bin Liu
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Wencong Wang
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Peyton Shieh
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Hung Nguyen
Departments: Department of Chemistry
Technology Areas: Therapeutics: Proteins & Antibodies, Small Molecules
Impact Areas: Healthy Living
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biomolecule-polymer-pharmaceutical agent conjugates for delivering the pharmaceutical agent
United States of America | Granted | 12,084,415 -
biomolecule-polymer-pharmaceutical agent conjugates for delivering the pharmaceutical agent
China | Published application -
biomolecule-polymer-pharmaceutical agent conjugates for delivering the pharmaceutical agent
European Patent Convention | Published application -
biomolecule-polymer-pharmaceutical agent conjugates for delivering the pharmaceutical agent
United States of America | Published application
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