METHODS FOR IDENTIFYING CHIMERIC ANTIGEN RECEPTOR-TARGETING LIGANDS AND USES THEREOF

Exclusively Licensed

The disclosure features chimeric antigen receptor (CAR) ligands, methods for making the same, and immunomodulatory compositions comprising the CAR ligands. The disclosure also features compositions and methods of using the immunomodulatory compositions, for example, to stimulate activation of CAR expressing cells.

Researchers

Darrell J Irvine / Benjamin Cossette / Leyuan Ma / Naveen Mehta / Karl Dane Wittrup

Departments: David H Koch Institute for Integrative Cancer Res, Department of Chemical Engineering
Technology Areas: Biotechnology: DNA & RNA Editing / Diagnostics: Assays / Drug Discovery and Research Tools: Cell Interrogation, Genomics & Proteomics / Therapeutics: Cell Based Therapy, Proteins & Antibodies
Impact Areas: Healthy Living

  • methods for identifying chimeric antigen receptor-targeting ligands and uses thereof
    United States of America | Published application

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