Nanobody Based Imaging and Targeting of ECM in Disease and Development
Exclusively Licensed
Invention type: Technology
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Case number: #19830HWJQ
Methods for developing disease-related nanobodies and related products and kits are provided. The disease- specific proteins are extracellular matrix (ECM) proteins, domains or epitopes that are associated with various aspects of disease and are not present, or are present in very low quantities, in non-diseased individuals. Highly effective nanobodies capable of specifically binding to these ECM protein epitopes useful in in vivo imaging assays, the detection, diagnosis and treatment of diseases as well as monitoring therapeutic progress in a patient with a disease are provided herein.
Researchers
Richard Hynes
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Yushu Xie
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Noor Jailkhani
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Hidde Ploegh
Departments: Department of Biology
Technology Areas: Biotechnology: Sensors & Monitoring / Sensing & Imaging: Imaging / Therapeutics: Proteins & Antibodies
Impact Areas: Healthy Living
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nanobody based imaging and targeting of ecm in disease and development
Japan | Granted | 7,644,441 -
nanobody based imaging and targeting of ecm in disease and development
United States of America | Granted | 11,597,769 -
nanobody based imaging and targeting of ecm in disease and development
United States of America | Published application -
nanobody based imaging and targeting of ecm in disease and development
Japan | Published application -
nanobody based imaging and targeting of ecm in disease and development
China | Published application -
nanobody based imaging and targeting of ecm in disease and development
European Patent Convention | Published application
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