A Booster Vaccine for CAR-T Cells

Exclusively Licensed

The disclosure describes amphiphilic ligand conjugates comprising a chimeric antigen receptor (CAR) ligand, a lipid (diacyl lipid), a linker (hydrophilic polymers, hydrophilic amino acids, polysaccharides), compositions and methods of using the constructs are claimed, for example, to stimulate proliferation of CAR expressing cells.

Researchers

Darrell J Irvine / Leyuan Ma

Technology Areas: Chemicals & Materials: Polymers / Therapeutics: Cell Based Therapy, Proteins & Antibodies
Impact Areas: Healthy Living

  • compositions for chimeric antigen receptor t cell therapy and uses thereof
    Hong Kong | Published application
  • compositions for chimeric antigen receptor t cell therapy and uses thereof
    Australia | Pending
  • compositions for chimeric antigen receptor t cell therapy and uses thereof
    Canada | Published application
  • compositions for chimeric antigen receptor t cell therapy and uses thereof
    China | Published application
  • compositions for chimeric antigen receptor t cell therapy and uses thereof
    European Patent Convention | Published application
  • compositions for chimeric antigen receptor t cell therapy and uses thereof
    Japan | Granted | 7,654,240
  • compositions for chimeric antigen receptor t cell therapy and uses thereof
    Korea (south) | Published application
  • compositions for chimeric antigen receptor t cell therapy and uses thereof
    Mexico | Granted | 426,727
  • compositions for chimeric antigen receptor t cell therapy and uses thereof
    New Zealand | Pending
  • compositions for chimeric antigen receptor t cell therapy and uses thereof
    Russian Federation | Granted | 2,819,805
  • compositions for chimeric antigen receptor t cell therapy and uses thereof
    Japan | Published application
  • compositions for chimeric antigen receptor t cell therapy and uses thereof
    New Zealand | Pending
  • compositions for chimeric antigen receptor t cell therapy and uses thereof
    Mexico | Published application
  • compositions for chimeric antigen receptor t cell therapy and uses thereof
    United States of America | Published application

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