Darrell J Irvine

Professor, Mat'l Sci & Eng and Biological Eng
Department
David H Koch Institute for Integrative Cancer Res
Technology Areas
Chemicals & Materials: Nanotechnology & Nanomaterials, Polymers, Catalysis & Synthesis, Metals / Drug Delivery: Microparticles & Nanoparticles, Vectors & Virus like Particles / Therapeutics: Cell Based Therapy, Proteins & Antibodies, Vaccines, Nucleic Acids, Small Molecules / Drug Discovery and Research Tools: Antibodies, Genomics & Proteomics, Cell Interrogation / Biotechnology: Synthetic Biology, Biomedical Devices & Systems, Sensors & Monitoring, DNA & RNA Editing, Cell Separation, Biomanufacturing / Diagnostics: Assays, Imaging Agents / Biomaterials & Bioelectronics: Health Monitoring
Impact Areas
Healthy Living, Advanced Materials, Uncharted Frontiers

Technologies

Vaccine Formulation Containing Dynamically Stabilized Immunostimulatory Oligonucleotide Micelles

Exclusively Licensed Technology / Case number: #15453H
Darrell J Irvine / Haipeng Liu
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living

Alum Binding Proteins

Exclusively Licensed Technology, Tangible Property / Case number: #21571H
Darrell J Irvine / Yash Agarwal / Tyson Moyer / Karl Dane Wittrup
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living

A Booster Vaccine for CAR-T Cells

Exclusively Licensed Technology / Case number: #19933H
Darrell J Irvine / Leyuan Ma
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living

METHODS FOR IDENTIFYING CHIMERIC ANTIGEN RECEPTOR-TARGETING LIGANDS AND USES THEREOF

Exclusively Licensed Technology / Case number: #22227H
Darrell J Irvine / Benjamin Cossette / Leyuan Ma / Naveen Mehta / Karl Dane Wittrup
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

RNA-based Logic Circuits with RNA Binding Proteins, Aptamers and Small Molecules

Exclusively Licensed Technology / Case number: #16631HJ
Darrell J Irvine / Kei Endo / Hirohide Saito / Tyler Wagner / Jacob Becraft / Katie Bodner / Tasuku Kitada / Velia Siciliano / Maria Hottelet Foley / Liliana Wroblewska / Ron Weiss
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Enhancement of Peptide Antigenicity for T Cell Priming Using Albumin Binding Peptides

Exclusively Licensed Technology / Case number: #19388H
Darrell J Irvine / Rebecca Holden / Kelly Moynihan / Bradley L. Pentelute
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Probing and Manipulating Cell Functions Through Intracellular Delivery

Exclusively Licensed Technology / Case number: #17162HJ
Robert Langer / Sophia Liu / Megan Heimann / George Hartoularos / Shirley Mao / Gregory Szeto / Armon Sharei / Ulrich Von Andrian / Pamela Basto / Siddharth Jhunjhunwala / Darrell J Irvine / Klavs F. Jensen
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Stochastic Barcoding Method for Single-Cell Tracking

Exclusively Licensed Technology / Case number: #16514H
Darrell J Irvine / Marc Castellarnau / Gregory Szeto / J. Christopher Love / Joel Voldman
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living

Synthetic Oncolytic LNP-Replicon RNA for Cancer Immunotherapy

Exclusively Licensed Technology / Case number: #21306HJQ
Darrell J Irvine / Noor Momin / Yingzhong Li / Yizhou Dong / Ron Weiss / Karl Dane Wittrup
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living

An Amphiphilic Mimotope Vaccine to Enhance FDA-Approved Anti-CD19 CAR T Therapy

Exclusively Licensed Technology / Case number: #22096H
Darrell J Irvine / Benjamin Cossette / Leyuan Ma / Naveen Mehta / Karl Dane Wittrup
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

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