Darrell J Irvine

Professor, Mat'l Sci & Eng and Biological Eng
Department
David H Koch Institute for Integrative Cancer Res
Technology Areas
Chemicals & Materials: Nanotechnology & Nanomaterials, Polymers, Catalysis & Synthesis, Metals / Drug Delivery: Microparticles & Nanoparticles, Vectors & Virus like Particles / Therapeutics: Cell Based Therapy, Proteins & Antibodies, Vaccines, Nucleic Acids, Small Molecules / Drug Discovery and Research Tools: Antibodies, Genomics & Proteomics, Cell Interrogation / Biotechnology: Synthetic Biology, Biomedical Devices & Systems, Sensors & Monitoring, DNA & RNA Editing, Cell Separation / Diagnostics: Assays, Imaging Agents / Biomaterials & Bioelectronics: Health Monitoring
Impact Areas
Healthy Living, Advanced Materials, Uncharted Frontiers

Technologies

Scalable and High throughput Assembly of Layer-by-Layer Nanoparticles

Technology / Case number: #25554H
Ivan Pires / Darrell J Irvine / Paula Hammond
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
License

Methods to Specifically Profile Protease Activity at Lymph Nodes

Technology / Case number: #18619H
Andrew Warren / Jaideep Dudani / Naveen Mehta / Sangeeta Bhatia / Darrell J Irvine / Karl Dane Wittrup
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
License

Lipid Anchorage of Cytokines onto Layer-by-Layer Nanoparticles

Technology / Case number: #25070H
Ivan Pires / Darrell J Irvine / Paula Hammond
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Cell-Surface Anchored Cytokine Therapy

Technology, Tangible Property / Case number: #25245H
Luciano Santollani / Darrell J Irvine / Karl Dane Wittrup
Technology Areas: Therapeutics
Impact Areas: Healthy Living
License

Optimized Alum-Anchored HIV Env Immunogens

Technology / Case number: #24972HJ
Kristen Rodrigues / Christopher Cottrell / Jon Steichen / William Schief / Darrell J Irvine
Technology Areas: Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Single-Dose Combination Immunotherapy Augments Responses to Checkpoint Blockades for the Treatment of Cancer

Technology / Case number: #21150H
Chensu Wang / Darrell J Irvine / Karl Dane Wittrup
Technology Areas: Therapeutics
Impact Areas: Healthy Living
License

Uses of Amphiphiles in Immune Cell Therapy and Compositions Therefore

Technology / Case number: #21411H
Peter DeMuth / Darrell J Irvine
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

STING Agonist Delivery by Lipid Nanodiscs for Tumor Immunotherapy

Technology / Case number: #21441HJ
Eric Dane / Masanori Okaniwa / Darrell J Irvine
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Intra-Tumoral Injection of Cytotoxic Chemotherapy-Treated Tumor Cells in Combination with Systemic Immune Checkpoint Blockade for Cancer Treatment

Technology / Case number: #21498H
Ganapathy Sriram / Lauren Milling / Darrell J Irvine / Michael Yaffe
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
License

Control Replication and Transcription of Self-Replicating RNA in Responses to Small Molecule TMP

Technology / Case number: #22331H
Ron Weiss / Yingzhong Li / Jan Lonzaric / Parisa Yousefpour / Darrell J Irvine
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

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