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"Click-Type" Modifications of Peptides via SNAr Reaction of Thiols with Fluorinated Aromatic Molecules

Exclusively Licensed Technology / Case number: #15765
Stephen Buchwald / Chi Zhang / Yekui Zou / Alexander Spokoyny / Bradley L. Pentelute
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living

End-Modified Poly(b-amino ester)s

Non-Exclusively Licensed Technology / Case number: #12049Q
Robert Langer / Gregory Zugates / Andreas Zumbuehl / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
License

Method for Examining Podocyte Foot Processes in Human Renal Samples Using Conventional Optical Microscopy

Non-Exclusively Licensed Technology, Tangible Property / Case number: #18385TEJ
Edward Stuart Boyden / Octavian Bucur / Andrew Beck / Yongxin Zhao
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Sensing & Imaging
Impact Areas: Healthy Living
License

Monolithic 3D Integration of Massively Parallel Sensing Over Logic

Non-Exclusively Licensed Technology / Case number: #20160
Max Shulaker / Mindy Bishop
Technology Areas: Chemicals & Materials / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living, Connected World
License

Modifications and Coatings to Improve Biocompatibility of Neurological Implants

Exclusively Licensed Technology / Case number: #19323J
Robert Langer / Robert Hevner / Samuel Browd / Brian Hanak / William Shain / Omid Veiseh / Daniel Anderson
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials

Powder Handling Free Continuous Process for Making a Solution or Suspension into Pharmaceutical Tablets

Exclusively Licensed Technology / Case number: #14666
T. Alan Hatton / Emily Chang / Keith Forward / Blair Brettmann / Yi Du / Nikhil Padhye / Won Kim / Ki Tae Kim / James Evans / Salvatore Mascia / Himanshu Dhamankar / Ryan Slaughter / Allan S. Myerson / Mao Wang / Bernhardt Trout / Gregory C Rutledge / Jung-Hoon Chun
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living, Advanced Materials

Adhesive Microstructures with Thin Glue Coating

Exclusively Licensed Technology / Case number: #15983J
Robert Langer / Maria Jose Pereira / Woo-Kyung Cho / Jeffrey Michael Karp
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living, Advanced Materials

Self-lubricating Surfaces for Food Packaging and Food Processing Equipment

Technology / Case number: #15511
Kripa K Varanasi / Brian Solomon / Rajeev Dhiman / Jonathan Smith / Adam Paxson / Christopher Love
Technology Areas: Agriculture & Food / Chemicals & Materials
Impact Areas: Healthy Living, Sustainable Future
License

Enhanced Polypeptide Synthesis by Inline Reagent Pretreatment

Exclusively Licensed Technology / Case number: #17541
Klavs F. Jensen / Alexander Mijalis / Dale Thomas / Mark Simon / Bradley L. Pentelute / Patrick Heider / Andrea Adamo
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials

Microbial Engineering for the Production of Chemical and Pharmaceutical Products from Isoprenoid Pathway

Exclusively Licensed Technology, Tangible Property / Case number: #13905J
Gregory Stephanopoulos / Heng Phon Too / Parayil Ajikumar
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living

Method for Screening Libraries of Enzymes with Improved Catalytic Properties or Altered Substrate Specificity Using Microwells for the Spatial Separation of Cells Producing the Enzymes

Exclusively Licensed Technology / Case number: #12967WJ
Kerry Love / J. Christopher Love
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Therapeutics
Impact Areas: Healthy Living

Multi-Layered Injectable Self-Assembling Peptide Scaffold Hydrogels for Long-Term Sustained Release of Human Antibodies

Exclusively Licensed Technology / Case number: #15537XE
Shuguang Zhang / Sotirios Koutsopoulos
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials

Bioadhesive with Triggerable On-Demand Detachment

Exclusively Licensed Technology / Case number: #22423
Xuanhe Zhao / Xiaoyu Chen / Hyunwoo Yuk
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials

Microbial Production of Glucaric Acid

Exclusively Licensed Technology / Case number: #13147
Tae Moon / Sang Hwal Yoon / Kristala L Jones Prather
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living

Shear-thinning Injectable Hydrogels for Multi-stage Drug Delivery

Exclusively Licensed Technology / Case number: #16764
Robert Langer / Mark Tibbitt / Eric Appel
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials

In Situ Curing Hydrophobic Tissue Adhesive

Exclusively Licensed Technology / Case number: #16181J
Robert Langer / Yuhan Lee / Nora Lang / Maria Jose Pereira / Pedro Del Nido / Jeffrey Michael Karp
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials

Direct Tablet Formation by Electrospinning Onto a Rod Drawn Into a Die to Strip Off and Compact Material Into a Tablet

Non-Exclusively Licensed Technology / Case number: #17321
Alexander Slocum / Indrani Bhattacharyya / Nicholas Sondej / Bernhardt Trout / Gregory C Rutledge
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Industrial Engineering & Automation
Impact Areas: Healthy Living
License

Elastomer-Hydrogel Hybrids with Robust Interfaces and Functional Microstructures

Exclusively Licensed Technology / Case number: #18522
Xuanhe Zhao / Hyunwoo Yuk
Technology Areas: Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials

Modified Alginates for Islet Encapsulation and Diabetes Treatment

Exclusively Licensed Technology / Case number: #14528JQ
Robert Langer / Arturo Vegas / Kaitlin Bratlie / Minglin Ma / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials

Swellable, Structurally Homogeneous Hydrogel for Expansion and Nanoscale Imaging of Biological Samples

Non-Exclusively Licensed Technology / Case number: #19849TE
Edward Stuart Boyden / Ruixuan Gao / Linyi Gao / Chih-Chieh (Jay) Yu
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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