Powder Handling Free Continuous Process for Making a Solution or Suspension into Pharmaceutical Tablets

Exclusively Licensed

Layer processing for pharmaceuticals, and related systems, methods, and articles are generally described. In some embodiments, ingestible pharmaceutical products (e.g., tablets) can be formed by processing one or more layers containing a pharmaceutically active composition. For example, at least one layer containing a pharmaceutically active composition can be manipulated (e.g., folded, rolled, stacked, etc.) such that the average thickness of the product formed by the manipulation is at least about two times the average thickness of the portions of the layer(s) used to form the product. In some embodiments, after the layer is manipulated, it can be processed (e.g., cut, coated, etc.) to form a final product such as, for example, a tablet.

Researchers

T. Alan Hatton / Emily Chang / Keith Forward / Blair Brettmann / Yi Du / Nikhil Padhye / Won Kim / Ki Tae Kim / James Evans / Salvatore Mascia / Himanshu Dhamankar / Ryan Slaughter / Allan S. Myerson / Mao Wang / Bernhardt Trout / Gregory C Rutledge / Jung-Hoon Chun

Departments: Department of Chemical Engineering, Laboratory for Manufacturing and Productivity
Technology Areas: Biotechnology: Biomanufacturing / Chemicals & Materials: Catalysis & Synthesis / Industrial Engineering & Automation: Manufacturing & Equipment

  • layer processing for pharmaceuticals
    Canada | Granted | 2,834,212
  • layer processing for pharmaceuticals
    United States of America | Granted | 9,205,089

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