Direct Tablet Formation by Electrospinning Onto a Rod Drawn Into a Die to Strip Off and Compact Material Into a Tablet

Non-Exclusively Licensed

Methods and systems for manufacturing a tablet are generally provided. Certain embodiments comprise electrodepositing (e.g., electrospinning) a material (e.g., the tablet material, for example, within a fluid) onto a substrate. The substrate can be, for example, an elongated rod. In some such embodiments, after material has been electrodeposited onto the substrate, a die comprising a cavity and the substrate can be moved relative to each other such that the electrodeposited material is at least partially stripped from the substrate and/or at least partially deposited into the cavity of the die. Some embodiments comprise compressing the material in the cavity to form a tablet.

Researchers

Alexander Slocum / Indrani Bhattacharyya / Nicholas Sondej / Bernhardt Trout / Gregory C Rutledge

Departments: Department of Mechanical Engineering, Department of Chemical Engineering
Technology Areas: Biotechnology: Biomanufacturing / Chemicals & Materials: Nanotechnology & Nanomaterials, Polymers / Drug Delivery: Microparticles & Nanoparticles / Industrial Engineering & Automation: Manufacturing & Equipment
Impact Areas: Healthy Living

  • methods and systems for manufacturing a tablet
    United States of America | Granted | 10,053,798
  • methods and systems for manufacturing a tablet
    Patent Cooperation Treaty | Published application

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