Microbial Production of Glucaric Acid

Exclusively Licensed

The invention relates to the production of glucuronic and glucaric acid in cells through recombinant expression of myo-inositol 1 -phosphate synthase, myo-inositol oxygenase and uronate dehydrogenase. Cloning and characterization of the gene encoding uronate dehydrogenase is also disclosed.

Researchers

Tae Moon / Sang Hwal Yoon / Kristala L Jones Prather

Departments: Department of Chemical Engineering
Technology Areas: Biotechnology: Biomanufacturing, DNA & RNA Editing, Synthetic Biology / Chemicals & Materials: Catalysis & Synthesis
Impact Areas: Healthy Living

  • cellular production of glucaric acid
    Netherlands | Granted | 2,274,417
  • cellular production of glucaric acid
    Korea (south) | Granted | 10
  • cellular production of glucaric acid
    Brazil | Granted | 0
  • cellular production of glucaric acid
    Canada | Granted | 2,720,526
  • cellular production of glucaric acid
    China | Granted | 200,980,120,748
  • cellular production of glucaric acid
    Japan | Granted | 6,196,016
  • cellular production of glucaric acid through recombinant expression of uronate dehydrogenase and myo-inositol oxygenase
    United States of America | Granted | 8,835,147
  • cellular production of glucaric acid
    Germany | Granted | 2,274,417
  • cellular production of glucaric acid
    Denmark | Granted | 2,274,417
  • cellular production of glucaric acid
    France | Granted | 2,274,417
  • cellular production of glucaric acid
    United Kingdom | Granted | 2,274,417
  • cellular production of glucaric acid
    Italy | Granted | 2,274,417

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