Modifications and Coatings to Improve Biocompatibility of Neurological Implants

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Neurological implants whose surfaces have been chemically and covalently modified to impart beneficial properties to the neurological implants are described. The neurological implants possess improved biocompatibility compared to a corresponding neurological implant that lacks the chemical modification. Following implantation in a subject, the surface-modified neurological implants induce a lower-foreign body response, compared to a corresponding unmodified product.

Researchers

Robert Langer / Robert Hevner / Samuel Browd / Brian Hanak / William Shain / Omid Veiseh / Daniel Anderson

Departments: Office of the Institute Professors, Department of Chemical Engineering
Technology Areas: Biomaterials & Bioelectronics: Medical Device Coatings / Biotechnology: Biomedical Devices & Systems / Chemicals & Materials: Polymers

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    United States of America | Granted | 11,318,231

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