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Invention Disclosure: Kinetic Sensing, Signal Generation, Feature Extraction, and Pattern Recognition for Control of Autonomous Wearable Leg Devices

Technology / Case number: #18945TE
Luke Mooney / Matthew Carney / Roman Stolyarov / Cameron Taylor / Hugh Herr
Technology Areas: Biotechnology / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Pulsing Light to Promote Recovery from Amblyopia

Technology / Case number: #25767P
Mark Bear / Francis Reilly-Andujar
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

Estimating Contractile Reserve using a Mechanical Circulatory Support Device

Technology / Case number: #25817J
Elazer Edelman / Steven Keller / Ahmad El Katerji / Jerald Curran
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
License

Transdermal Optogenetic Peripheral Nerve Stimulation

Technology / Case number: #18928TE
Anthony Zorzos / Benjamin Maimon / Hugh Herr
Technology Areas: Biotechnology
Impact Areas: Healthy Living, Uncharted Frontiers
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Optimized Opsin Trafficking with Fluorescence-Dead Protein Fusions

Technology / Case number: #18783TE
Edward Boyden / Kiryl Piatkevich / Aimei Yang / Demian Park
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods And Compositions For High-Throughput Compressed Screening For Therapeutics

Technology / Case number: #21936RH
Alexander Shalek / Benjamin Mead / Conner Kummerlowe / No Inventor
Technology Areas: Computer Science / Therapeutics
Impact Areas: Healthy Living
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A Stretchable, Wearable Ultrasound Transducer for Wide-Scale Breast Cancer Data Collection

Technology / Case number: #20934TE
Canan Dagdeviren / Lin Zhang
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
License

TOX Inhibitor and Molecular Glue

Technology / Case number: #25241
Angela Koehler / Bocheng Wu
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Methods for the Treatment of Trinucleotide Repeat Expansion Disorders Associated with FAN1 activity via Targeting of FAN1 Splice Site Inhibitory Sequences

Technology / Case number: #24829
Christopher Ng / David Housman
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Method for Zero Phase-Lag Real-Time Computation of Hilbert Transform and Analytic Signal

Technology / Case number: #18073TEJ
Edward Boyden / Nir Grossman / David Wang
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Neuromechanical Interventions for the Mitigation of Limb Pathology

Technology / Case number: #18430TE
Anthony Zorzos / Benjamin Maimon / Matthew Carty / Tyler Clites / Jean-Francois Duval / Shriya Srinivasan / Hugh Herr
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Methods and Apparatuses to Track Hand Configurations based on Ultrasound Signals

Technology / Case number: #25586
Xuanhe Zhao / Gengxi Lu
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Computer Science
Impact Areas: Healthy Living, Connected World
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Closed-Loop Noninvasive Brain Stimulation with Simultaneous Imaging to Control Cerebrospinal Fluid Flow in Humans

Technology / Case number: #25482
Laura Lewis / Joshua Levitt
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living
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Ingestible Electronics Integrated with Flexible Measurement Electrodes for Gastrointestinal Bioelectric Sensing

Technology / Case number: #23241
Carlo Giovanni Traverso / Robert Langer / Siheng You / So-Yoon Yang / Adam Gierlach / George Selsing
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science
Impact Areas: Healthy Living, Advanced Materials
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Bioelectronic Devices to Support Transplanted Cells in Vivo for Encapsulated Cell Therapies

Technology / Case number: #23269J
Suman Bose / Robert Langer / Siddharth Krishnan / Matthew Bochenek / Nima Khatib / Daniel Anderson
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living
License

A Wavemeter-Enabled Swept Source Raman Spectroscopy System

Technology / Case number: #20066
Amir Atabaki / William Herrington / Rajeev Ram
Technology Areas: Biotechnology / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living, Connected World
License

Software and Methods for Controlling Neural Responses in Deep Brain Regions

Technology / Case number: #20652M
James DiCarlo / Pouya Bashivan / Kohitij Kar
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Computer Science
Impact Areas: Healthy Living, Uncharted Frontiers
License

Genotype-Directed Local Delivery of Targeted Therapeutics at the Tumor Margin

Technology / Case number: #19863J
Carlo Giovanni Traverso / Ameya Kirtane / Daniel Cahill / Ganesh Shankar / Robert Langer
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Formulated, Biodegradable Polymeric Nanoparticles for Nucleic Acid Delivery to Non-Liver Targets

Technology / Case number: #19802
Kevin Kauffman / James Kaczmarek / Asha Patel / Luke Rhym / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Lipid Compositions for Delivery of Therapeutic Agents Comprising Cationic Lipids

Technology / Case number: #23842J
Sho Toyonaga / Theresa Raimondo / Dennis Shi / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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