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Engineered Protein for Rapid, Efficient, and Selective Capture of Pathogen-Specific Antibodies on Cellulose

Non-Exclusively Licensed Technology / Case number: #22394
Hadley Sikes / Seunghyeon Kim / Eric Miller
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Nanobody Based Imaging and Targeting of ECM in Disease and Development

Exclusively Licensed Technology / Case number: #19830HWJQ
Richard Hynes / Yushu Xie / Noor Jailkhani / Hidde Ploegh
Technology Areas: Biotechnology / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living

Vaccine Formulation Containing Dynamically Stabilized Immunostimulatory Oligonucleotide Micelles

Exclusively Licensed Technology / Case number: #15453H
Darrell J Irvine / Haipeng Liu
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living

Novel Memory-like NK Cell Based Chimeric Antigen Receptor (CAR) Targeting Mutated NPM1 in Myeloid Malignancies

Exclusively Licensed Technology / Case number: #22960J
Jianzhu Chen / James Ham / Han Dong / Jerome Ritz / Rizwan Romee / Guozhu Xie
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Delivery Systems for Anti-Retroviral Drugs

Technology / Case number: #18813J
Robert Langer / Omar Abouzid / Ameya Kirtane / Mousa Jafari / Tyler Grant / Stacy Mo / Angela Diciccio / Dean Glettig / Shiyi Zhang / Andrew Bellinger / Giovanni Traverso
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Self-Assembling Drug Delivery Devices For Gastrointestinal Retention

Technology / Case number: #17002J
Robert Langer / Jiaqi Lin / Stacy Mo / Angela Diciccio / William Gates / Boris Nikolic / Phillip Eckhoff / Dean Glettig / Shiyi Zhang / Andrew Bellinger / Lowell Wood / Giovanni Traverso
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Combinatorial Optimization of Red-Shifted Opsin Molecules

Non-Exclusively Licensed Technology, Tangible Property / Case number: #14611TQE
Brian Chow / Amy Chuong / Nathan Klapoetke / Xue Han / Edward Stuart Boyden
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
License

SYNTHETIC HEPARIN MIMETICS AND USES THEREOF

Exclusively Licensed Technology / Case number: #22634HJQ
Christopher Chen / Jeroen Eyckmans / Jinling Yang / Linqing Li / Sangeeta Bhatia
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living

Versatile High Affinity Antibody to DOTA Chelates of Multiple Radionuclides

Exclusively Licensed Technology / Case number: #13506
Karl Dane Wittrup / Kelly Davis
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Single-Cell Encapsulated Bacteria

Non-Exclusively Licensed Technology / Case number: #18184
Robert Langer / Aaron Anselmo / Ana Jaklenec
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

Alum Binding Proteins

Exclusively Licensed Technology, Tangible Property / Case number: #21571H
Darrell J Irvine / Yash Agarwal / Tyson Moyer / Karl Dane Wittrup
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living

A Booster Vaccine for CAR-T Cells

Exclusively Licensed Technology / Case number: #19933H
Darrell J Irvine / Leyuan Ma
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living

Protein for Rapid, Efficient Capture of Tuberculosis Antigens from Urine

Non-Exclusively Licensed Technology / Case number: #19946
Hadley Sikes / Ki-Joo Sung / Eric Miller
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
License

Specific Viral Targeting of Hematopoietic Stem Cells via Engineering of Viral Tropism

Exclusively Licensed Technology / Case number: #22988JQ
Michael Birnbaum / Cassandra Burnett / Kole Roybal / Stephanie Gaglione / Connor Dobson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living

Tumor-Specific CAR-T Cell Therapy for Treating Acute Myeloid Leukemia

Exclusively Licensed Technology / Case number: #21827
Jianzhu Chen / Guozhu Xie
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Combined Inhibition of Polo-like kinase 1 (Plk1) and Microtubule Polymerization for the Treatment of Cancer

Exclusively Licensed Technology / Case number: #21961
Michael Yaffe / Jesse C Patterson / Brian A Joughin
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

METHODS FOR IDENTIFYING CHIMERIC ANTIGEN RECEPTOR-TARGETING LIGANDS AND USES THEREOF

Exclusively Licensed Technology / Case number: #22227H
Darrell J Irvine / Benjamin Cossette / Leyuan Ma / Naveen Mehta / Karl Dane Wittrup
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

RNA-based Logic Circuits with RNA Binding Proteins, Aptamers and Small Molecules

Exclusively Licensed Technology / Case number: #16631HJ
Darrell J Irvine / Kei Endo / Hirohide Saito / Tyler Wagner / Jacob Becraft / Katie Bodner / Tasuku Kitada / Velia Siciliano / Maria Hottelet Foley / Liliana Wroblewska / Ron Weiss
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Enhancement of Peptide Antigenicity for T Cell Priming Using Albumin Binding Peptides

Exclusively Licensed Technology / Case number: #19388H
Darrell J Irvine / Rebecca Holden / Kelly Moynihan / Bradley L. Pentelute
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Activation Induced Clipping System

Technology / Case number: #24546J
Jianzhu Chen / Alaa Ali / Rizwan Romee / Guozhu Xie
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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