Combinatorial Optimization of Red-Shifted Opsin Molecules
Non-Exclusively Licensed
Invention type: Technology, Tangible Property
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Case number: #14611TQE
Compositions and methods for altering cell activity and function by expressing a light-activated ion pump polypeptide in a cell and contacting the cell with light that activates the expressed light-activated ion pump polypeptide. In some aspects of the invention, a light-activated ion pump polypeptide is a modified haloarcula halorhodopsin polypeptide, for example, a modified Halo 57 polypeptide.
Researchers
Brian Chow
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Amy Chuong
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Nathan Klapoetke
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Xue Han
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Edward Stuart Boyden
Departments: Department of Brain and Cognitive Sciences
Technology Areas: Biotechnology: Synthetic Biology / Diagnostics: Imaging Agents / Sensing & Imaging: Imaging / Therapeutics: Cell Based Therapy, Proteins & Antibodies
Impact Areas: Healthy Living
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red-shifted opsin molecules and uses thereof
United States of America | Granted | 9,500,641 -
red-shifted opsin molecules and uses thereof
United States of America | Granted | 8,957,028 -
red-shifted opsin molecules and uses thereof
United States of America | Granted | 10,106,584
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