Specific Viral Targeting of Hematopoietic Stem Cells via Engineering of Viral Tropism

Exclusively Licensed Technology / Case number: #22988JQ
Michael Birnbaum / Cassandra Burnett / Kole Roybal / Stephanie Gaglione / Connor Dobson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living

Thermostabilization of Dry Lipid Nanoparticle Encapsulating mRNA using Polyvinylpyrrolidone and/or Polyvinyl Alcohol

Exclusively Licensed Technology / Case number: #22963
Robert Langer / John Daristotle / Maria Kanelli / Aurelien Vander Straeten / Morteza Sarmadi / Joseph Collins / Ana Jaklenec
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living

Synthetic Oncolytic LNP-Replicon RNA for Cancer Immunotherapy

Exclusively Licensed Technology / Case number: #21306HJQ
Darrell J Irvine / Noor Momin / Yingzhong Li / Yizhou Dong / Ron Weiss / Karl Dane Wittrup
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living

Novel RNA Modality for Translation in Eukaryotic Cells

Exclusively Licensed Technology / Case number: #19874Q
Daniel Anderson / Robert Wesselhoeft / Piotr Kowalski
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Lipid/Polymer Nanoformulations with Alphavirus Replicon RNA

Exclusively Licensed Technology / Case number: #17996H
Darrell J Irvine / Yuan Zhang / Mariane Melo / Tasuku Kitada / Ron Weiss
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living

Barcoded Combinatorial Genetic Screening with CRISPR-CAS

Exclusively Licensed Technology / Case number: #17251
Timothy K Lu / Ching Gee (Gigi) Choi / Alan Siu Lun Wong
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Probing and Manipulating Cell Functions Through Intracellular Delivery

Exclusively Licensed Technology / Case number: #17162HJ
Robert Langer / Sophia Liu / Megan Heimann / George Hartoularos / Shirley Mao / Gregory Szeto / Armon Sharei / Ulrich Von Andrian / Pamela Basto / Siddharth Jhunjhunwala / Darrell J Irvine / Klavs F. Jensen
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Light-gated Ion Channels with Fast Kinetics and High Sensitivity

Exclusively Licensed Technology / Case number: #16950TEJ
Gane Wong / Adam Cohen / Daniel Hochbaum / Yongku Cho / Nathan Klapoetke / Edward Stuart Boyden / Brian Chow
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living

RNA-based Logic Circuits with RNA Binding Proteins, Aptamers and Small Molecules

Exclusively Licensed Technology / Case number: #16631HJ
Darrell J Irvine / Kei Endo / Hirohide Saito / Tyler Wagner / Jacob Becraft / Katie Bodner / Tasuku Kitada / Velia Siciliano / Maria Hottelet Foley / Liliana Wroblewska / Ron Weiss
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Natural Evolution of H5N1 Hemagglutinin Amino Acid Sequence and Its Implication on Human Adaptation and Antigenicity

Exclusively Licensed Technology / Case number: #16072
Rahul Raman / Nathan Stebbins / Kannan Tharakaraman / Karthik Viswanathan / Ram Sasisekharan
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
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