Thermostabilization of Dry Lipid Nanoparticle Encapsulating mRNA using Polyvinylpyrrolidone and/or Polyvinyl Alcohol

Exclusively Licensed

Disclosed are compositions that stabilize (e.g., thermo-stabilize) biological agents, such as IIiRNA. Also disclosed are
methods of administering and using said compositions.

Researchers

Robert Langer / John Daristotle / Maria Kanelli / Aurelien Vander Straeten / Morteza Sarmadi / Joseph Collins / Ana Jaklenec

Departments: Office of the Institute Professors, David H Koch Institute for Integrative Cancer Res
Technology Areas: Drug Delivery: Microparticles & Nanoparticles / Therapeutics: Nucleic Acids, Vaccines
Impact Areas: Healthy Living

  • compositions and methods for stabilizing biomolecules
    United States of America | Published application
  • compositions and methods for stabilizing biomolecules
    European Patent Convention | Published application
  • compositions and methods for stabilizing biomolecules
    India | Pending

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