Natural Evolution of H5N1 Hemagglutinin Amino Acid Sequence and Its Implication on Human Adaptation and Antigenicity

Exclusively Licensed

The present invention provides, among other things, technologies and methodologies for detection, treatment, and/or prevention of influenza transmission and/or infection. The present invention also provides technologies for monitoring influenza HA variants with particular degrees of susceptibility to mutation for human adaptation.

Researchers

Rahul Raman / Nathan Stebbins / Kannan Tharakaraman / Karthik Viswanathan / Ram Sasisekharan

Departments: Department of Biological Engineering, School of Engineering
Technology Areas: Diagnostics: Assays / Therapeutics: Nucleic Acids, Proteins & Antibodies

  • human adaptation of h5 influenza
    Japan | Granted | 6,518,597
  • human adaptation of h5 influenza
    Russian Federation | Granted | 2,708,447
  • human adaptation of h5 influenza
    Germany | Granted | 2,953,967
  • human adaptation of h5 influenza
    France | Granted | 2,953,967
  • human adaptation of h5 influenza
    United Kingdom | Granted | 2,953,967
  • human adaptation of h5 influenza
    Hong Kong | Granted | 1,215,257
  • human adaptation of h5 influenza
    Canada | Granted | 2,898,633
  • human adaptation of h5 influenza
    Australia | Granted | 2,014,214,754
  • human adaptation of h5 influenza
    India | Granted | 534,921
  • human adaptation of h5 influenza
    Hong Kong | Granted | 1,218,923
  • human adaptation of h5 influenza
    Brazil | Granted | 0
  • human adaptation of h5 influenza
    Singapore | Granted | 11,201,505,744
  • human adaptation of h5 influenza
    China | Granted | 105,263,954
  • human adaptation of h5 influenza
    European Patent Convention | Granted | 2,953,967

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