Peptide Nucleic Acid Functionalized Hydrogel Microneedles for Sampling and Detection of Interstitial Fluid Nucleic Acids

The present disclosure relates to a device, comprising a base and a plurality of microneedles attached to the base, wherein each microneedle has an outer surface; the outer surface of at least one microneedle being coated with a composition comprising at least one polymer and least one Peptide Nucleic Acid (PNA). The present disclosure additionally relates to a method of detecting an analyte in interstitial fluid (ISF), comprising contacting the device to a subject, for example, to human skin.

Researchers

Yin Hao Chang / Sylvain Ladame / Dana Al Sulaiman / Darrell Irvine

Departments: Department of Biological Engineering
Technology Areas: Biotechnology: Biomedical Devices & Systems, Sensors & Monitoring / Drug Discovery and Research Tools: Genomics & Proteomics / Therapeutics: Nucleic Acids
Impact Areas: Healthy Living

  • peptide nucleic acid functionalized hydrogel microneedles for sampling and detection of interstitial fluid nucleic acids
    United States of America | Published application
  • peptide nucleic acid functionalized hydrogel microneedles for sampling and detection of interstitial fluid nucleic acids
    European Patent Convention | Published application
  • peptide nucleic acid functionalized hydrogel microneedles for sampling and detection of interstitial fluid nucleic acids
    United States of America | Published application

License this technology

Interested in this technology? Connect with our experienced licensing team to initiate the process.

Sign up for technology updates

Sign up now to receive the latest updates on cutting-edge technologies and innovations.

More Technologies