Immune Pharmacytes: Nanoparticle-Modified Leukocytes for Immunotherapy

The invention provides compositions and methods for delivering agents to localized regions, tissues, or organs in vivo by conjugating agent-loaded nanoparticles to cells having homing capability. The agents may be therapeutic or diagnostic agents such as cancer chemotherapeutic agents and imaging agents respectively.

Researchers

Matthias Stephan / Jae Hyun (James) Moon / Anna Bershteyn / Darrell Irvine

Departments: Department of Biological Engineering
Technology Areas: Diagnostics: Imaging Agents / Drug Delivery: Microparticles & Nanoparticles / Therapeutics: Small Molecules
Impact Areas: Healthy Living

  • methods and compositions for localized agent delivery
    United States of America | Granted | 9,283,184
  • methods and compositions for localized nanoparticle delivery to a tumor
    European Patent Convention | Granted | 2,398,466
  • methods and compositions for localized agent delivery
    United States of America | Granted | 9,393,199
  • methods and compositions for localized agent delivery
    European Patent Convention | Published application
  • methods and compositions for localized nanoparticle delivery to a tumor
    France | Granted | 2,398,466
  • methods and compositions for localized nanoparticle delivery to a tumor
    Germany | Granted | 2,398,466
  • methods and compositions for localized nanoparticle delivery to a tumor
    Ireland | Granted | 2,398,466
  • methods and compositions for localized nanoparticle delivery to a tumor
    Italy | Granted | 2,398,466
  • methods and compositions for localized nanoparticle delivery to a tumor
    Spain | Granted | 2,398,466
  • methods and compositions for localized nanoparticle delivery to a tumor
    Switzerland | Granted | 2,398,466
  • methods and compositions for localized nanoparticle delivery to a tumor
    United Kingdom | Granted | 2,398,466
  • methods and compositions for localized agent delivery
    Hong Kong | Published application
  • methods and compositions for localized agent delivery
    United States of America | Pending

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