Methods to Specifically Profile Protease Activity at Lymph Nodes
Invention type: Technology
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Case number: #18619H
In some aspects, the disclosure provides compositions and methods for detecting and monitoring the activity of pro teases in vivo using affinity assays. The disclosure relates, in part, to the discovery that biomarker nanoparticles targeted to the lymph nodes of a subject are useful for the diagnosis and monitoring of certain medical conditions (e.g., metastatic cancer, infection with certain pathogenic agents).
Researchers
Departments: Health Sciences and Technology Program, Department of Biological Engineering, Department of Chemical Engineering
Technology Areas: Biomaterials & Bioelectronics: Health Monitoring / Biotechnology: Sensors & Monitoring / Chemicals & Materials: Nanotechnology & Nanomaterials / Diagnostics: Assays
Impact Areas: Healthy Living
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methods to specifically profile protease activity at lymph nodes
United States of America | Granted | 11,448,643 -
methods to specifically profile protease activity at lymph nodes
European Patent Convention | Published application -
methods to specifically profile protease activity at lymph nodes
United States of America | Published application
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