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Using over Wnt ing to Treat Colon Cancer: Small Molecule GSK3 Inhibitors and Novel Protein Isolation

Technology / Case number: #23378J
George Eng / Omer Yilmaz / Jonathan Braverman
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Single-Cell RNA Sequencing Using Click-Chemistry

Technology / Case number: #20396
Dig Mahat / Phillip Sharp
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Receptor Specific Peptides for Bcl-2 Family Anti-apoptotic Proteins

Technology / Case number: #20337J
Amy Keating / Gevorg Grigoryan / Justin Jenson / Vincent Xue / Jianfu Zhou
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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A Bioinspired Design of Self-Adjuvanted C3d-Fusion SARS-CoV-2 mRNA Vaccines

Technology / Case number: #23326
Robert Langer / Bowen Li / Allen Jiang / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Luminal Unfolding Micro-Injectors for Drug Delivery

Technology / Case number: #20106JQ
Carlo Giovanni Traverso / Daniel Minahan / Alex Abramson / Ester Caffarel Salvador / Vance Soares / Robert Langer
Technology Areas: Biotechnology
Impact Areas: Healthy Living, Uncharted Frontiers
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Quick Release Capsules for Small Intestine Delivery

Technology / Case number: #20105J
Carlo Giovanni Traverso / Daniel Minahan / Alex Abramson / Niclas Roxhed / Ester Caffarel Salvador / David Dellal / Vance Soares / Robert Langer / Christoph Winfried Johannes Steiger / Morten Frederiksen
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Closed-Loop Intramuscular Motility Prosthesis, Submucosal Neuromodulation Device and Minimally Invasive Endoscopic Implantation Tool

Technology / Case number: #23258J
Polina Anikeeva / Carlo Giovanni Traverso / Shriya Srinivasan / Robert Langer / Marc-Joseph Antonini
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science
Impact Areas: Healthy Living
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Ingestible Chemical Energy Harvesting System with Extended Lifetime

Technology / Case number: #23174
Carlo Giovanni Traverso / Jason Li / So-Yoon Yang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Closed-Loop Ingestible Robot for Radiation and Chemical Sensing

Technology / Case number: #22735
Carlo Giovanni Traverso / Hen Wei Huang / James Byrne
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Healthy Living, Uncharted Frontiers
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Electronic Sensing/Valve Application (Concept 3a Needle-less Drug Delivery)

Technology / Case number: #22659
Carlo Giovanni Traverso / Niclas Roxhed / Siheng You / Graham Arrick / Torben Sebastia Last
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Parameter Space for Jetting in the GI Submucosa

Technology / Case number: #22633J
Carlo Giovanni Traverso / Jorrit Water / Jacob Wainer / Brian Mouridsen / Mette Poulsen / Declan Gwynne / Graham Arrick / Cody Cleveland / Drago Sticker / Aghiad Ghazal / Jacob Pyung Hwa Jepsen / Dan Sorensen
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Endovascular Injectable Stents for Cardiovascular Drug Delivery

Technology / Case number: #22578J
Carlo Giovanni Traverso / Sahab Babaee / Mazen Albaghdadi / Mohammed Chowdhury
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living, Advanced Materials
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Ingestible Electronic Pills for Hormone Modulation

Technology / Case number: #22427
Carlo Giovanni Traverso / Khalil Ramadi / James McRae
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Glucose-Responsive Glucagon Formulations for Closed-Loop Prophylactic Treatment of Hypoglycemia

Technology / Case number: #21838J
Carlo Giovanni Traverso / Robert Langer / Jason Li / Se Jun Lee
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Cellular Backpacks for Drug Delivery Across the Blood-Brain Barrier

Technology / Case number: #18547J
Roberta Polak / Elena Batrakova / Matthew Haney / Yuling Zhao / Natalya Klyachko / Michael Rubner / Robert Cohen
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Method of Forming Topcoat for Patterning

Technology / Case number: #18405QJ
Priya Moni / Do Han Kim / Paul Nealey / Hyo Seon Suh / Karen Gleason
Technology Areas: Chemicals & Materials / Electronics & Photonics
Impact Areas: Advanced Materials
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Spray-Coating Method with Particle Alignment Control

Technology / Case number: #18817J
Dayong Chen / Roberta Polak / Kenan Song / Khalid Askar / Michael Rubner / Robert Cohen
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
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A Metal-Organic Framework Electrode for Li-Ion Supercapacitors

Technology / Case number: #21224J
Mircea Dinca / Jinhu Dou / Michal Borysiewicz / Riccardo Parenti / Harish Banda
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
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Liquid Metal Printing

Technology / Case number: #21880J
Skylar Tibbits / Jared Laucks / Schendy Kernizan / Bjorn Sparrman / Masaki Otomori / Miya Nobuhiro
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Multiscale Porous High-Temperature Heat Exchanger

Technology / Case number: #21240J
Evelyn Wang / Lin Zhao / Bikramjit Bhatia / Arny Leroy / Kyle Wilke / Lenan Zhang / Xiangyu Li / Jeffrey Youngblood / Rodney Trice / Chad Wilson / Olivia Brandt / Rodrigo Guerra
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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