Closed-Loop Intramuscular Motility Prosthesis, Submucosal Neuromodulation Device and Minimally Invasive Endoscopic Implantation Tool

Articles and systems configured for treating GI motility disorders are generally provided. In some embodiments, an article comprising one or more electrodes (with both sensing and stimulating capabilities) may be configured to stimulate one or more tissues in the GI tract, electrically and/or chemically, to modulate peristalsis and/or allow neuromodulation. In some embodiments, a system comprises a controller that allows for close-loop operation of the article, e.g., such that the article may stimulate (e.g., via a feedback loop) the one or more organs in the GI tract upon receiving sensed parameters in the GI tract. In some embodiments, an implantation tool comprising a sensor may allow for submucosal or intramuscular implantation of an article. The implantation tool and the article may be useful for, for example, as a general platform for delivery of treating GI motility disorders and/or neuromodulation of the GI tract.

Researchers

Robert Langer / Marc-Joseph Antonini / Shriya Sruthi Srinivasan / Giovanni Traverso / Polina Anikeeva

Departments: Office of the Institute Professors, David H Koch Institute for Integrative Cancer Res, Department of Mechanical Engineering, Department of Materials Science and Engineering
Technology Areas: Biotechnology: Biomedical Devices & Systems, Prostheses / Chemicals & Materials: Polymers / Computer Science: Bioinformatics
Impact Areas: Healthy Living

  • neuromodulation devices and related methods
    Patent Cooperation Treaty | Published application
  • neuromodulation devices and related methods
    United States of America | Published application

License this technology

Interested in this technology? Connect with our experienced licensing team to initiate the process.

Sign up for technology updates

Sign up now to receive the latest updates on cutting-edge technologies and innovations.