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Programmable Gene Insertion with Paired Targeting Guides

Technology / Case number: #24104
Omar Abudayyeh / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Luminescent Sensors for Electrophiles

Technology / Case number: #11833
Timothy Manning Swager / Koushik Venkatesan / Samuel Thomas
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Climate Stabilization, Healthy Living
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Universal RNA-Binding Protein Based on the Pumilio Domain Architecture

Technology / Case number: #17629TE
Edward Stuart Boyden / Daniel Martin Alarcon / Katarzyna Adamala
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Single-Walled Carbon Nanotube Based Hydrogels for In Vivo Glucose Detection

Technology / Case number: #13588
Michael S. Strano / Hyeonseok Yoon / Rene Ortiz Garcia / Ardemis Boghossian / Jin Ho Ahn / Jingqing Zhang / Paul Barone
Technology Areas: Biotechnology / Chemicals & Materials / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Electrical and Mechanical Assembly of High-Density Three-Dimensional Micro-Fabricated Arrays

Technology / Case number: #15252TE
Clifton Fonstad / Jorg Scholvin / Anthony Zorzos / Edward Stuart Boyden
Technology Areas: Biotechnology / Energy & Distribution
Impact Areas: Healthy Living
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Biomarkers and Therapeutics for Autism Spectrum Disorders

Technology / Case number: #13589P
Mriganka Sur / Damon Page
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Generation of Specialized, High-Value Cells and Tissues from Human Induced Pluripotent Stem Cells by Recapitulating Early Embryogenesis Using Gata Factor-Induced Endoderm

Technology, Tangible Property / Case number: #16205
Ron Weiss / Mohammad Reza Ebrahimkhani / Patrick Guye
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Human Skin Movement and Strain-Field Calculations and Modeling

Technology / Case number: #14811
Dava Newman / Ashley Wessendorf
Technology Areas: Biotechnology / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living
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Method for the Characterization and Differentiation of Material Surfaces Using Compound Responses of Mechanically Driven Cells

Technology / Case number: #17585J
Dick Yue / Xiaoying Zhu / Roland Bouffanais
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Method for High Efficiency in Vivo Gene Editing

Technology / Case number: #17117H
Tyler Jacks / Hao Yin / Joseph Dorkin / Wen Xue / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Programmable Drug Delivery Profiles of Tumor-Targeted Bacteria

Technology / Case number: #15818H
Sangeeta Bhatia / Tal Danino
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Cellular Surface Engineering via Multilayered Polymer Nanostructures

Technology / Case number: #12846
Robert Cohen / Albert Swiston / Darrell J Irvine / Michael F Rubner
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Split Peroxidases for Detection of Protein-Protein Interactions

Technology / Case number: #16082
Alice Ting / Jeffrey Martell
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
License

System for Portable Body Surface Acquisition

Technology / Case number: #17269
Luca Giancardo / Aurelien Bourquard / Tobias Hahn / Carlos Sanchez Mendoza
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
License

Force Controlled Ultrasound Probe

Technology / Case number: #14088
Brian Anthony
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
License

High-Throughput Screening Metabolic Flux Biosensor

Technology / Case number: #16813JW
Gerald Fink / Jose Avalos / Gregory Stephanopoulos
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

Epigenetic Mechanisms Re-Establish Access to Long-Term Memory After Neuronal Loss

Technology / Case number: #12467HPBJ
Stuart Schreiber / Stephen Haggarty / Li-Huei Tsai / Andre Fischer / Weiping Tang
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Ultrasonic Method for Measuring Concentrations of Particles, Cells and Islets in Suspension

Technology / Case number: #11886J
Clark Colton / Steven Africk
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
License

Method and Apparatus for Imaging the Eye from a Distance

Technology / Case number: #17933TE
Ramesh Raskar / Tristan Swedish / Karin Roesch
Technology Areas: Biotechnology / Communication Systems / Sensing & Imaging
Impact Areas: Healthy Living, Connected World
License

In Vivo Targeting of T-Cells with Antibody- and Cytokine Conjugated Liposomes

Technology / Case number: #16405H
Darrell J Irvine / Brandon Kwong / Yuan Zhang / Yiran Zheng
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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