3-D Holographic Imaging Flow Cytometry

Non-Exclusively Licensed

Refractive index of biological specimens is a source of intrinsic contrast that can be explored without any concerns of photobleaching or harmful effects caused by extra contrast agents. This feature also contains rich information that can be related to the metabolism of cells at the cellular and subcellular levels. The present invention relates to systems and methods that can provide, without any moving parts, the 3-D refractive index map of continuously flowing biological samples in a micro-fluidic channel, for example.

Researchers

Ramachandra Dasari / Yongjin Sung / Niyom Lue / Zahid Yaqoob / Peter So

Departments: Lincoln Laboratory, Department of Mechanical Engineering
Technology Areas: Biotechnology: Biomedical Devices & Systems, Sensors & Monitoring / Diagnostics: Assays / Drug Discovery and Research Tools: Cell Interrogation / Sensing & Imaging: Chemical & Radiation Sensing
Impact Areas: Healthy Living

  • 3-d holographic imaging flow cytometry
    Japan | Granted | 6,801,846
  • 3-d holographic imaging flow cytometry
    Germany | Granted | 2,954,309
  • 3-d holographic imaging flow cytometry
    United Kingdom | Granted | 2,954,309
  • 3-d holographic imaging flow cytometry
    Japan | Granted | 6,958,964
  • 3-d holographic imaging continuous flow cytometry
    United States of America | Granted | 10,670,510
  • 3-d holographic imaging flow cytometry
    European Patent Convention | Granted | 2,954,309

License this technology

Interested in this technology? Connect with our experienced licensing team to initiate the process.

Sign up for technology updates

Sign up now to receive the latest updates on cutting-edge technologies and innovations.

More Technologies