Lipomer Nanoparticles for Highly Efficient SiRNA Delivery
Exclusively Licensed
Invention type: Technology
/
Case number: #14649
The present invention provides inventive conjugated polyethyleneimine (PEI) polymers and conjugated aza-macrocycles (collectively referred to herein as “conjugated lipomers” or “lipomers”) containing one or more groups of the formula (iii) wherein R3 and R4 are as defined herein. Also provided are compositions comprising the inventive conjugated lipomers, and methods of preparation and use.
Researchers
Robert Langer
/
James Dahlman
/
Avraham Schroeder
/
Christopher Levins
/
Daniel Anderson
Departments: Office of the Institute Professors, Department of Chemical Engineering
Technology Areas: Biotechnology: DNA & RNA Editing / Drug Delivery: Microparticles & Nanoparticles / Therapeutics: Nucleic Acids
Impact Areas: Healthy Living
-
conjugated lipomers and uses thereof
United States of America | Published application -
conjugated lipomers and uses thereof
United States of America | Granted | 9,238,716 -
conjugated lipomers and uses thereof
Canada | Granted | 2,831,392 -
conjugated lipomers and uses thereof
European Patent Convention | Granted | 2,691,443 -
conjugated lipomers and uses thereof
United States of America | Granted | 10,117,934 -
conjugated lipomers and uses thereof
United States of America | Granted | 10,933,139 -
conjugated lipomers and uses thereof
Switzerland | Granted | 2,691,443 -
conjugated lipomers and uses thereof
Czech Republic | Granted | 2,691,443 -
conjugated lipomers and uses thereof
Germany | Granted | 2,691,443 -
conjugated lipomers and uses thereof
Denmark | Granted | 2,691,443 -
conjugated lipomers and uses thereof
Finland | Granted | 2,691,443 -
conjugated lipomers and uses thereof
France | Granted | 2,691,443 -
conjugated lipomers and uses thereof
United Kingdom | Granted | 2,691,443 -
conjugated lipomers and uses thereof
Italy | Granted | 2,691,443 -
conjugated lipomers and uses thereof
Liechtenstein | Granted | 2,691,443 -
conjugated lipomers and uses thereof
Netherlands | Granted | 2,691,443 -
conjugated lipomers and uses thereof
Norway | Granted | 2,691,443 -
conjugated lipomers and uses thereof
Poland | Granted | 2,691,443 -
conjugated lipomers and uses thereof
Sweden | Granted | 2,691,443
License this technology
Interested in this technology? Connect with our experienced licensing team to initiate the process.
Sign up for technology updates
Sign up now to receive the latest updates on cutting-edge technologies and innovations.