Large Field of View, Single Cell Detection System

Exclusively Licensed

A method and system for medical imaging employs an excitation source configured to cause an object having a plurality of cells to at least one of emit, reflect, and fluoresce light. An optical receptor is employed that is configured to receive the light from the object. A filter assembly receives the light from the optical receptor and filters the light. An image processor having a field of view (FOV) substantially greater than a diameter of a cell of the object and an analysis resolution substantially matched to the diameter of a cell of the object that receives the filtered light from the filter and analyzes the filtered light corresponding to each cell in the FOV. A feedback system is provided that is configured to provide an indication of a state of each cell in the FOV and a location of a cell in the FOV meeting a predetermined condition.

Researchers

Moungi G Bawendi / David Kirsch / W. David Lee / Lisa Marshall / Jorge Ferrer

Departments: Department of Chemistry, Institute for Medical Engineering and Science
Technology Areas: Biotechnology: Biomedical Devices & Systems, Sensors & Monitoring / Diagnostics: Assays / Drug Discovery and Research Tools: Cell Interrogation / Sensing & Imaging: Imaging, Optical Sensing
Impact Areas: Healthy Living

  • system and method for large field of view, single cell analysis
    United States of America | Published application
  • system and method for large field of view, single cell analysis
    United States of America | Granted | 8,983,581
  • system and method for large field of view, single cell analysis
    United States of America | Granted | 11,730,371
  • system and method for large field of view, single cell analysis
    United States of America | Granted | 11,266,313

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