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Amino Acid, Peptide, Polypeptide-Lipids (APPL) Derivatives and Uses Thereof

Technology / Case number: #14910Q
Kevin Love / Arturo Vegas / Delai Chen / Yi Chen / Yizhou Dong / Yunlong Zhang / Akinleye Alabi / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Lipid-Like Materials for Applications in siRNA Delivery

Technology / Case number: #15420
Kathryn Whitehead / Arturo Vegas / Yunlong Zhang / Joseph Dorkin / Robert Langer / Daniel Anderson
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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1,3,5-triazinane-2,4,6-trione (TNT) Derivatives and Uses Thereof

Technology / Case number: #15446
Delai Chen / Yizhou Dong / Ahmed Eltoukhy / Joseph Dorkin / Akinleye Alabi / Hao Yin / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Self- Regulated Peptide Hydrogel for Closed Loop Insulin Delivery

Technology / Case number: #15056J
Zhen Gu / Alex Aimetti / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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CD80 is a Biomarker of p53 Activity and a Target for Cancer Therapy

Technology / Case number: #15386H
David Feldser / Leah Schmidt / Tyler Jacks
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Polyamine-Fatty Acid Derived Lipidoids for Drug Delivery

Technology / Case number: #16367
Joseph Dorkin / Owen Fenton / Rebecca McClellan / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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1,2-Aminoalcohol Lipidoids (II)

Technology / Case number: #13661Q
Kerry Mahon / Kevin Love / Christopher Levins / Kathryn Whitehead / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Valency Controlled Quantum Dots with Tunable Number of Biotin Binding Sites

Technology / Case number: #12606B
Mark Howarth / Wenhao Liu / Moungi G Bawendi / Alice Ting
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Electronics & Photonics / Therapeutics
Impact Areas: Healthy Living
License

Methods and Compositions for Protein Labeling Using Lipoic Acid Ligases

Technology / Case number: #12773
Hemanta Baruah / Yoon-Aa Choi / Marta Fernandez Suarez / Alice Ting
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Self-Assembling Peptides Incorporating Modifications and Methods of Use Thereof

Technology / Case number: #13846XE
Yoshiyuki Kumada / Shuguang Zhang
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living
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Formulation of Polymeric Particles for Prostate Cancer Targeting

Technology / Case number: #12162J
Jianjun Cheng / Benjamin Teply / Stephen Zale / Robert Langer / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Antigenically Intact Hemagglutinin in Circulating Avian and Swine Influenza Viruses and Potential for H3N2 Pandemic

Technology / Case number: #16225
Kannan Tharakaraman / Rahul Raman / Ram Sasisekharan
Technology Areas: Therapeutics
Impact Areas: Healthy Living
License

Immune Pharmacytes: Nanoparticle-Modified Leukocytes for Immunotherapy

Technology / Case number: #13509H
Matthias Stephan / Jae Hyun (James) Moon / Anna Bershteyn / Darrell J Irvine
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Lithium-Ion Fiber Battery

Technology / Case number: #16676
Benjamin Grena / Yoel Fink
Technology Areas: Chemicals & Materials / Drug Delivery / Energy & Distribution
Impact Areas: Healthy Living, Advanced Materials
License

High Throughput Isolation of Antigen-Specific Antibodies and Cells

Technology / Case number: #16927J
Han Wei Hou / Aniruddh Sarkar / Galit Alter / Jongyoon Han
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

Salmochelin-Antibiotic Conjugates for Targeting Gram-Negative Pathogens

Technology / Case number: #16939
Tengfei Zheng / Phoom Chairatana / Elizabeth M. Nolan
Technology Areas: Therapeutics
Impact Areas: Healthy Living
License

Extended Transient Transfection by Repeated Delivery of RNA

Technology / Case number: #13415
Matthew Angel / Mehmet Yanik
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Surface Binding of Nanoparticles-Based Drug Delivery to Tissue

Technology / Case number: #15731
Rohit N Karnik / Cliff Wong / Ambika Bajpayee / Alan Grodzinsky / Moungi G Bawendi
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Nanoparticle Technology for Immune Response Against Small and Macromolecules-Method of Preparation and Uses Thereof

Technology / Case number: #13399J
Frank Alexis / Pamela Basto / Ulrich Von Andrian / Elliot Moseman / Matteo Iannacone / Jinjun Shi / Elena Tonti / Robert Langer / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Glycan-Receptor Binding of the Novel Influenza A Virus H7N9 Hemagglutinin

Technology / Case number: #16359
Akila Jayaraman / Kannan Tharakaraman / Nathan Stebbins / Rahul Raman / Ram Sasisekharan
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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