Valency Controlled Quantum Dots with Tunable Number of Biotin Binding Sites

A controlled valency semiconductor nanocrystal can have a desired number of compounds associated with it. The semiconductor nanocrystal can have exactly one compound associated with it, and the compound can have exactly one binding site for an affinity target. The semiconductor nanocrystal can be used to image single copies of cell-surface proteins.

Researchers

Mark Howarth / Wenhao Liu / Moungi Bawendi / Alice Ting

Departments: Department of Chemistry
Technology Areas: Biotechnology: Sensors & Monitoring / Chemicals & Materials: Nanotechnology & Nanomaterials / Diagnostics: Imaging Agents / Electronics & Photonics: Semiconductors / Therapeutics: Proteins & Antibodies
Impact Areas: Healthy Living

  • controlled modification of semiconductor nanocrystals
    European Patent Convention | Granted | 2,165,185

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