Methods and Compositions for Protein Labeling Using Lipoic Acid Ligases

The invention provides compositions and methods of use thereof for labeling peptide and proteins in vitro or in vivo. The methods described herein employ lipoic acid ligase or mutants thereof, and lipoic acid analogs recognized by lipoic acid ligase and lipoic acid ligase mutants.

Researchers

Hemanta Baruah / Yoon-Aa Choi / Marta Fernandez Suarez / Alice Ting

Technology Areas: Biotechnology: Sensors & Monitoring / Diagnostics: Imaging Agents / Therapeutics: Nucleic Acids, Proteins & Antibodies
Impact Areas: Healthy Living

  • methods and compositions for protein labeling using lipoic acid ligases
    United States of America | Granted | 8,137,925

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