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Amino Acid, Peptide, Polypeptide-Lipids (APPL) Derivatives and Uses Thereof

Technology / Case number: #14910Q
Kevin Love / Arturo Vegas / Delai Chen / Yi Chen / Yizhou Dong / Yunlong Zhang / Akinleye Alabi / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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1,3,5-triazinane-2,4,6-trione (TNT) Derivatives and Uses Thereof

Technology / Case number: #15446
Delai Chen / Yizhou Dong / Ahmed Eltoukhy / Joseph Dorkin / Akinleye Alabi / Hao Yin / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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CD80 is a Biomarker of p53 Activity and a Target for Cancer Therapy

Technology / Case number: #15386H
David Feldser / Leah Schmidt / Tyler Jacks
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Valency Controlled Quantum Dots with Tunable Number of Biotin Binding Sites

Technology / Case number: #12606B
Mark Howarth / Wenhao Liu / Moungi G Bawendi / Alice Ting
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Electronics & Photonics / Therapeutics
Impact Areas: Healthy Living
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Methods and Compositions for Protein Labeling Using Lipoic Acid Ligases

Technology / Case number: #12773
Hemanta Baruah / Yoon-Aa Choi / Marta Fernandez Suarez / Alice Ting
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Self-Assembling Peptides Incorporating Modifications and Methods of Use Thereof

Technology / Case number: #13846XE
Yoshiyuki Kumada / Shuguang Zhang
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living
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Antigenically Intact Hemagglutinin in Circulating Avian and Swine Influenza Viruses and Potential for H3N2 Pandemic

Technology / Case number: #16225
Kannan Tharakaraman / Rahul Raman / Ram Sasisekharan
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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High Throughput Isolation of Antigen-Specific Antibodies and Cells

Technology / Case number: #16927J
Han Wei Hou / Aniruddh Sarkar / Galit Alter / Jongyoon Han
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Salmochelin-Antibiotic Conjugates for Targeting Gram-Negative Pathogens

Technology / Case number: #16939
Tengfei Zheng / Phoom Chairatana / Elizabeth M. Nolan
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Extended Transient Transfection by Repeated Delivery of RNA

Technology / Case number: #13415
Matthew Angel / Mehmet Yanik
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Nanoparticle Technology for Immune Response Against Small and Macromolecules-Method of Preparation and Uses Thereof

Technology / Case number: #13399J
Frank Alexis / Pamela Basto / Ulrich Von Andrian / Elliot Moseman / Matteo Iannacone / Jinjun Shi / Elena Tonti / Robert Langer / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Glycan-Receptor Binding of the Novel Influenza A Virus H7N9 Hemagglutinin

Technology / Case number: #16359
Akila Jayaraman / Kannan Tharakaraman / Nathan Stebbins / Rahul Raman / Ram Sasisekharan
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Biomarkers and Therapeutics for Autism Spectrum Disorders

Technology / Case number: #13589P
Damon Page / Mriganka Sur
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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In Vivo Targeting of T-Cells with Antibody- and Cytokine Conjugated Liposomes

Technology / Case number: #16405H
Yiran Zheng / Yuan Zhang / Brandon Kwong / Darrell J Irvine
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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A Single-Walled Carbon Nano-Tube/Chitosan Hydrogel Array for the Label-Free, Optical Detection of Protein-Protein Interactions

Technology / Case number: #14201
Michael S. Strano / Jong Ho Kim / Paul Barone / Jin Ho Ahn / Nigel Reuel
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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The Site-Specific Incorporation of a Redox-Active and Chemically-Reactive Amino Acid into Proteins in E. Coli

Technology / Case number: #12973J
Peter Schultz / Jianming Xie / Mohammad Seyedsayamdost / Clement Tsz Chan / Lital Alfonta / JoAnne Stubbe
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Design and Applications of a Set of Antibody Cysteine Variants

Technology / Case number: #13713JQ
Naresh Chennamsetty / Bernhard Helk / Vladimir Voynov / Veysel Kayser / Bernhardt Trout
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Extra Cellular Matrix Proteins and Cancer

Technology / Case number: #15501JHR
Steven Carr / Richard Hynes / Alexandra Naba / Karl Clauser / Kenneth Tanabe
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Tricalcium Phosphate Binding Peptides and Proteins

Technology / Case number: #13913J
Luis Alvarez / Yadir Guerrero / Linda Stockdale / Jaime Rivera / Linda Griffith
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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  • Women's Health
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Nanoparticle Delivery of Adjuvant-Method of Preparation and Uses Thereof

Technology / Case number: #13344J
Frank Alexis / Pamela Basto / Ulrich Von Andrian / Elliot Moseman / Matteo Iannacone / Jinjun Shi / Elena Tonti / Robert Langer / Omid Farokhzad
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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