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Engineered Protein for Rapid, Efficient, and Selective Capture of Pathogen-Specific Antibodies on Cellulose

Non-Exclusively Licensed Technology / Case number: #22394
Hadley Sikes / Seunghyeon Kim / Eric Miller
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Nanobody Based Imaging and Targeting of ECM in Disease and Development

Exclusively Licensed Technology / Case number: #19830HWJQ
Richard Hynes / Yushu Xie / Noor Jailkhani / Hidde Ploegh
Technology Areas: Biotechnology / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living

Delivery Systems for Anti-Retroviral Drugs

Technology / Case number: #18813J
Robert Langer / Omar Abouzid / Ameya Kirtane / Mousa Jafari / Tyler Grant / Stacy Mo / Angela Diciccio / Dean Glettig / Shiyi Zhang / Andrew Bellinger / Giovanni Traverso
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Self-Assembling Drug Delivery Devices For Gastrointestinal Retention

Technology / Case number: #17002J
Robert Langer / Jiaqi Lin / Stacy Mo / Angela Diciccio / William Gates / Boris Nikolic / Phillip Eckhoff / Dean Glettig / Shiyi Zhang / Andrew Bellinger / Lowell Wood / Giovanni Traverso
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Specific Viral Targeting of Hematopoietic Stem Cells via Engineering of Viral Tropism

Exclusively Licensed Technology / Case number: #22988JQ
Michael Birnbaum / Cassandra Burnett / Kole Roybal / Stephanie Gaglione / Connor Dobson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living

METHODS FOR IDENTIFYING CHIMERIC ANTIGEN RECEPTOR-TARGETING LIGANDS AND USES THEREOF

Exclusively Licensed Technology / Case number: #22227H
Darrell J Irvine / Benjamin Cossette / Leyuan Ma / Naveen Mehta / Karl Dane Wittrup
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

RNA-based Logic Circuits with RNA Binding Proteins, Aptamers and Small Molecules

Exclusively Licensed Technology / Case number: #16631HJ
Darrell J Irvine / Kei Endo / Hirohide Saito / Tyler Wagner / Jacob Becraft / Katie Bodner / Tasuku Kitada / Velia Siciliano / Maria Hottelet Foley / Liliana Wroblewska / Ron Weiss
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Probing and Manipulating Cell Functions Through Intracellular Delivery

Exclusively Licensed Technology / Case number: #17162HJ
Robert Langer / Sophia Liu / Megan Heimann / George Hartoularos / Shirley Mao / Gregory Szeto / Armon Sharei / Ulrich Von Andrian / Pamela Basto / Siddharth Jhunjhunwala / Darrell J Irvine / Klavs F. Jensen
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Methods and Compositions for Ameliorating or Inhibiting Decline in Memory or Intelligence or Improving Same

Exclusively Licensed Technology / Case number: #12090Q
Richard Wurtman / Lisa Teather / Judith Wurtman
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living

Rapid Solid Phase Peptide Synthesizer

Exclusively Licensed Technology / Case number: #15911
Klavs F. Jensen / Mark Simon / Bradley L. Pentelute / Patrick Heider / Andrea Adamo
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Kinase Sensing via Hydroxyquinoline-Sensitized Europium Chelates

Exclusively Licensed Technology / Case number: #18646QJ
Barbara Imperiali / Juan Gonzalez Vera
Technology Areas: Diagnostics / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living

A New Platform for Combination Drug Delivery: Nanoparticles Built from a Platinum Crosslinker

Exclusively Licensed Technology / Case number: #16248
Jeremiah A. Johnson / Longyan Liao
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials

Enabling the Injectability of Concentrated Drug Formulations and Solid Particles via Droplet Lubrication

Exclusively Licensed Technology / Case number: #20744
Kripa K Varanasi / Maxime Costalonga / Vishnu Jayaprakash
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living

"Click-Type" Modifications of Peptides via SNAr Reaction of Thiols with Fluorinated Aromatic Molecules

Exclusively Licensed Technology / Case number: #15765
Stephen Buchwald / Chi Zhang / Yekui Zou / Alexander Spokoyny / Bradley L. Pentelute
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living

End-Modified Poly(b-amino ester)s

Non-Exclusively Licensed Technology / Case number: #12049Q
Robert Langer / Gregory Zugates / Andreas Zumbuehl / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
License

Uses of Chemicals to Modulate GSK-3B/B-Catenin Signaling for Treatment of Bipolar Disorder and Other Brain Disorders

Technology / Case number: #13480BJ
Stephen Haggarty / Michael Lewis / Edward Holson / Qian Pan / Joshua Ketterman / Tracey Petryshen / Daniel Fass
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
License

Novel Full Spectrum Anti-Dengue Antibody

Exclusively Licensed Technology / Case number: #16643
Ram Sasisekharan / Kannan Tharakaraman
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Peptide and Protein Modification to Afford Sox-Based Kinase Sensors

Exclusively Licensed Technology / Case number: #12133Q
Barbara Imperiali / Dora Carrico-Moniz / Elvedin Lukovic
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Molecular Determinants of Human Adaptation of H5N1 Influenza A Virus Hemagglutinin

Exclusively Licensed Technology / Case number: #14274
Rahul Raman / Kannan Tharakaraman / Karthik Viswanathan / Ram Sasisekharan
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Combination Therapies for Prostate and Breast Cancer with Abiraterone

Exclusively Licensed Technology / Case number: #16690Q
Michael Yaffe / Jesse C Patterson
Technology Areas: Therapeutics
Impact Areas: Healthy Living

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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