A New Platform for Combination Drug Delivery: Nanoparticles Built from a Platinum Crosslinker
Described herein are platinum-based brush-arm star polymers (Pt-BASPs), or a pharmaceutical composition thereof, for delivery of platinum-based agents, such as cisplatin. Also provided are methods and kits involving the Pt-BASPs, or a pharmaceutical composition thereof, for treating proliferative diseases such as cancers (e.g., lung cancer, head-and-neck cancer, esophagus cancer, stomach cancer, breast cancer, pancreas cancer, liver cancer, kidney cancer, or prostate cancer) in a subject.
Researchers
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drug delivery polymer and uses thereof
United States of America | Granted | 10,159,749 -
drug delivery polymer and uses thereof
United States of America | Granted | 10,799,594 -
drug delivery polymer and uses thereof
France | Granted | 2,983,659 -
drug delivery polymer and uses thereof
Germany | Granted | 2,983,659 -
drug delivery polymer and uses thereof
Italy | Granted | 2,983,659 -
drug delivery polymer and uses thereof
Spain | Granted | 2,983,659 -
drug delivery polymer and uses thereof
United Kingdom | Granted | 2,983,659 -
drug delivery polymer and uses thereof
European Patent Convention | Granted | 2,983,659 -
drug delivery polymer and uses thereof
United States of America | Granted | 9,381,253
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