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Amino Acid, Peptide, Polypeptide-Lipids (APPL) Derivatives and Uses Thereof

Technology / Case number: #14910Q
Robert Langer / Akinleye Alabi / Yunlong Zhang / Yizhou Dong / Yi Chen / Delai Chen / Arturo Vegas / Kevin Love / Daniel Anderson
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Volume Contraction and Substrate Fluidization as a Means to Reduce Drag on Bodies Moving Through a Granular Substrate

Technology / Case number: #13498
Alexander Slocum / Amos Winter / Anette Hosoi
Technology Areas: Agriculture & Food / Industrial Engineering & Automation
Impact Areas: Sustainable Future
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Amplitude Spectroscopy of a Solid-State Artificial Atom

Technology / Case number: #13407L
Karl Berggren / Terry Orlando / Leonid Levitov / William Oliver / Sergio Valenzuela / Mark Rudner / David Berns
Technology Areas: Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Lipid-Like Materials for Applications in siRNA Delivery

Technology / Case number: #15420
Robert Langer / Joseph Dorkin / Yunlong Zhang / Arturo Vegas / Kathryn Whitehead / Daniel Anderson
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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2-Aminoindole-Class Antimalarials

Technology / Case number: #14097BJ
Jon Clardy / Elyse Bourque / Yibin Xiang / Renato Skerlj / Edmund Sybertz / Joseph Cortese / Mary Lynn Baniecki / Roger Wiegand / Dyann Wirth / Cassandra Celatka / Sameer Urgaonkar / Ralph Mazitschek
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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1,3,5-triazinane-2,4,6-trione (TNT) Derivatives and Uses Thereof

Technology / Case number: #15446
Robert Langer / Hao Yin / Akinleye Alabi / Joseph Dorkin / Ahmed Eltoukhy / Yizhou Dong / Delai Chen / Daniel Anderson
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Heterocycle-Modified Quinolines for Fluorescence-Based Protein Kinase Sensing

Technology / Case number: #13876
Barbara Imperiali / Juan Gonzalez Vera / Elvedin Lukovic
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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SNAPPLE - Sequencing-Mediated Numerical Analysis of Parallel Proximity Ligation Events

Technology / Case number: #13615B
Andreas Gnirke / Daniel Aird / Erez Lieberman
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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A Novel Injectable Thiol-Acrylate Poly(ethylene Glycol) Hydrogel for Sustained Release of Methylprednisolone Sodium Succinate

Technology / Case number: #14439J
Robert Langer / Jonathan Slotkin / Francis Reynolds / Timothy O'Shea / Daniel Siegwart / Christopher Pritchard / Eric Woodard / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Translocation of Non-Natural Chemical Entities Through Anthrax Protective Antigen Pore

Technology / Case number: #15639J
Bradley L. Pentelute / R. Collier / Gizem Akcay / Jingjing Ling / Amy Rabideau / Xiaoli Liao
Technology Areas: Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Novel Glucose-Responsive Insulin Formulations Using Chemically Modified Insulin Derivatives and Non-Covalent Insulin-Binding Molecules

Technology / Case number: #15976J
Robert Langer / Rosemary Kanasty / Matthew Webber / Kun Xue / Hung-Chieh (Danny) Chou / Benjamin Tang / Yunlong Zhang / Yair Levi / Arturo Vegas / Daniel Anderson
Technology Areas: Chemicals & Materials / Computer Science / Therapeutics
Impact Areas: Healthy Living
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Self Assembled RSV Nanoparticle Vaccines

Technology / Case number: #16549
Ram Sasisekharan / Aditya Raguram / Vidya Subramanian
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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sMutants of Channelrhodopsins with Altered Ion Selectivity

Technology / Case number: #16934TE
Edward Stuart Boyden / Fei Chen / Yongku Cho / Amy Chuong / Nathan Klapoetke
Technology Areas: Electronics & Photonics / Therapeutics
Impact Areas: Healthy Living
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Reversible and Ratiometric Sensing using Nanocrystals

Technology / Case number: #11693
Moungi G Bawendi / Rebecca Somers / Preston Snee / Daniel Nocera
Technology Areas: Biotechnology / Diagnostics / Electronics & Photonics / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Olfactory Receptor-Based Devices

Technology / Case number: #12776TE
Shuguang Zhang / Liselotte Kaiser / Joanke (Johanna) Bikker Graveland / Brian Cook / Andreas Mershin / Manu Prakash / David Kong / Yael Maguire
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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CD80 is a Biomarker of p53 Activity and a Target for Cancer Therapy

Technology / Case number: #15386H
Tyler Jacks / Leah Schmidt / David Feldser
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Polyamine-Fatty Acid Derived Lipidoids for Drug Delivery

Technology / Case number: #16367
Daniel Anderson / Rebecca McClellan / Owen Fenton / Joseph Dorkin
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Valency Controlled Quantum Dots with Tunable Number of Biotin Binding Sites

Technology / Case number: #12606B
Moungi G Bawendi / Wenhao Liu / Mark Howarth / Alice Ting
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Electronics & Photonics / Therapeutics
Impact Areas: Healthy Living
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Methods and Compositions for Protein Labeling Using Lipoic Acid Ligases

Technology / Case number: #12773
Alice Ting / Marta Fernandez Suarez / Yoon-Aa Choi / Hemanta Baruah
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Self-Assembling Peptides Incorporating Modifications and Methods of Use Thereof

Technology / Case number: #13846XE
Shuguang Zhang / Yoshiyuki Kumada
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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