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Manually Actuated Device Capable of On-demand/Programmed Pulsatile Drug Delivery

Technology / Case number: #21833JQ
Giovanni Traverso / Jason Li / Rebecca McManus / SeungHo Lee / Adam Wentworth / Qianqian Wan
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Multi-stable Device Configurations and Controls for Gastric Drug Delivery Devices

Technology / Case number: #22017J
Giovanni Traverso / Niclas Roxhed / Robert Langer / Morten Frederiksen / Jacob Wainer / Brian Mouridsen / Jesper Windum / Declan Gwynne / Graham Arrick / Yi Lu / Torben Sebastia Last / Adam Jun Bohr / Nikolaj Eusebius Jakobsen / Kuldeep Sanger / Jens Laursen / Ludwig Erik Aguilar
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Nucleotide Depletion as Differentiation Therapy in the Treatment of Cancer

Technology / Case number: #21131J
Matthew Vander Heiden / Peggy Hsu / David Sykes / Frances Diehl
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Flexible Electronics for Analyte Detection

Technology / Case number: #21994J
Giovanni Traverso / Robert Langer / Hen Wei Huang / Sean You / Luca Di Tizio
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Flower-Inspired System with Shape-Memory Torsion Springs

Technology / Case number: #20940J
Giovanni Traverso / Ester Caffarel Salvador / Robert Langer / Sahab Babaee / Simo Pajovic
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Tissue Platform and Machine Learning Algorithm for Drug-Drug Transporter Interaction Discovery

Technology / Case number: #21883J
Giovanni Traverso / Yunhua Shi / Vance Soares / Daniel Reker / Robert Langer
Technology Areas: Biomaterials & Bioelectronics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Polymers for Messenger RNA Delivery to the Lung

Technology / Case number: #19314
Kevin Kauffman / James Kaczmarek / Asha Patel / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Structure-Guided Chemical Modification of Guide RNA and its Applications

Technology / Case number: #19175V
Hao Yin / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Derivation of Enteroendocrine Cells and Insulin Expressing Cells

Technology / Case number: #18445J
Jeffrey Michael Karp / Xiaolei Yin / Robert Langer
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Implantable Devices and Methods for Evaluation of Active Agents

Technology / Case number: #17867J
Robert Tepper / Jason Fuller / Oliver Jonas / John Santini / No Inventor
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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sgRNA Chemical Modification for Efficient Gene Editing

Technology / Case number: #17805V
Hao Yin / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Motorized and Balloon Dynamic Satiety Stimulator

Technology / Case number: #25050J
Giovanni Traverso / Neil Jia
Technology Areas: Biotechnology / Industrial Engineering & Automation
Impact Areas: Healthy Living
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A Fully Implantable, Autonomous Closed-Loop System Capable of Long-Term Vital Signs Monitoring and Performing Lifesaving Treatment

Technology / Case number: #23387J
Giovanni Traverso / Hen Wei Huang / SeungHo Lee / Saurav Maji / Peter Chai / Tom Kerssemakers / Ian Ballinger / Anantha Chandrakasan
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science / Energy & Distribution
Impact Areas: Healthy Living, Advanced Materials
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DNA Based Immobilization for Improved Electrochemical Carbon Dioxide Reduction

Technology / Case number: #23961
Ariel Furst / Gang Fan
Technology Areas: Biotechnology / Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future
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Microbial Production of Alpha-Substituted 3-Hydroxy Acids from Glucose

Technology / Case number: #25163
Kristala L Jones Prather / K'yal Bannister
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Ionizable Lipids for Messenger RNA Delivery

Technology, Tangible Property / Case number: #24861
Jacob Witten / Idris Raji / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Generalizable, High-Throughput Method to Rapidly add Chemical Moieties to a Small Molecule Library

Technology / Case number: #22196J
Angela Koehler / Brice Curtin / Jasmin Kruell / Catherine Henry / Sebastian Pomplun / Christina Woo / Chia-fu Chang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Small Molecule Inhibitors of Interleukin-4

Technology / Case number: #22186J
Angela Koehler / Arturo Vegas / Shelby Doyle / Becky Leifer / Stephen Nestor / Kelly Tan / Luke Ceo / Daniel Sheehy / Sean Quinnell
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

Tough Hydrogel Pills Inflating 100 Times in Volume Within 10 Min

Technology / Case number: #20059
Xuanhe Zhao / Shaoting Lin / Hyunwoo Yuk / German Parada Hernandez / Xinyue Liu
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
License

Gastric Residence Electronics

Technology / Case number: #20092J
Giovanni Traverso / Yong Lin Kong / Robert Langer
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Communication Systems
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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