A Hybrid, Vector-Free, Microfluidic Delivery Platform for Engineering Cell Function
Exclusively Licensed
Invention type: Technology
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Case number: #17401
A microfluidic system for causing perturbations in a cell membrane includes (a) a microfluidic channel defining a lumen and configured such that a cell suspended in a buffer can pass there through, and (b) source or emitter of an energy field. The microfluidic channel may include a cell-deforming constriction. A diameter of the constriction may be a function of the diameter of the cell. Related apparatus, systems, techniques, and articles are also described.
Researchers
Robert Langer
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Xiaoyun Ding
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Armon Sharei
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Klavs F. Jensen
Departments: Office of the Institute Professors, Department of Chemical Engineering
Technology Areas: Biotechnology: Biomedical Devices & Systems, Synthetic Biology / Drug Discovery and Research Tools: Cell Interrogation
Impact Areas: Healthy Living
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disruption and field enabled delivery of compounds and compositions into cells
Japan | Granted | 7,591,265 -
disruption and field enabled delivery of compounds and compositions into cells
European Patent Convention | Published application -
disruption and field enabled delivery of compounds and compositions into cells
Canada | Granted | 2,964,138 -
disruption and field enabled delivery of compounds and compositions into cells
China | Granted | 0 -
disruption and field enabled delivery of compounds and compositions into cells
United States of America | Granted | 10,526,573 -
disruption and field enabled delivery of compounds and compositions into cells
Japan | Granted | 6,846,345
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