Somatic Opsins for Single Cell Resolution Optogenetics

Non-Exclusively Licensed

The invention, in some aspects, relates to polypeptide molecules and their encoding nucleic acid molecules and use of such molecules to target opsins to the soma of cells in which they are expressed. Compositions of the invention may be delivered to cells and subjects and used in methods to modulate electrical activity of cells in which they are expressed, and for treatment of diseases and conditions in subjects.

Researchers

Edward Stuart Boyden / Changyang Linghu / Or Shemesh

Departments: Department of Brain and Cognitive Sciences
Technology Areas: Biotechnology: Biomedical Devices & Systems, Sensors & Monitoring, Synthetic Biology / Diagnostics: Assays / Drug Discovery and Research Tools: Cell Interrogation / Sensing & Imaging: Optical Sensing
Impact Areas: Healthy Living

  • somatic opsins for single cell resolution optogenetics
    United States of America | Granted | 11,324,824

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