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A Generalizable, High-Throughput Method to Rapidly add Chemical Moieties to a Small Molecule Library

Technology / Case number: #22196J
Angela Koehler / Brice Curtin / Jasmin Kruell / Catherine Henry / Sebastian Pomplun / Christina Woo / Chia-fu Chang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Tough Hydrogel Pills Inflating 100 Times in Volume Within 10 Min

Technology / Case number: #20059
Xuanhe Zhao / Shaoting Lin / Hyunwoo Yuk / German Parada Hernandez / Xinyue Liu
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Gastric Residence Electronics

Technology / Case number: #20092J
Carlo Giovanni Traverso / Yong Lin Kong / Robert Langer
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Communication Systems
Impact Areas: Healthy Living
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Hybrid Materials with Living Cells and Tough Hydrogels

Technology / Case number: #18548
Timothy Lu / Xuanhe Zhao / Eleonore Tham / Xinyue Liu / Tzu-Chieh Tang
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Diagnostics / Therapeutics
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Flexible Piezoelectric Devices for Gastrointestinal Motility Sensing

Technology / Case number: #19910JQ
Carlo Giovanni Traverso / Canan Dagdeviren / Robert Langer
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living, Advanced Materials
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Single-shot 16-fold Expansion Microscopy (16ExM)

Technology / Case number: #24859MH
Edward Boyden / Laura Kiessling / Tay Won Shin / Shiwei Wang / Yixi Liu / Harley Yoder
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Clockwise Learning Task

Technology / Case number: #25128M
Georgios Papageorgiou / Ann Graybiel
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Uncharted Frontiers
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Engineered Synthetic IRES with Improved and Robust Translation in Circular RNA

Technology / Case number: #25300YJ
James Collins / Katherine Ilia / Shiva Razavi / Kehan Zhang / Xiaoyu Chen / Makoto Lalwani / Yu Li / Nayoung Kim
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Reconstituted Lipoprotein Particles to Rescue Lipid Defects in the Alzheimer's Brain

Technology / Case number: #25445P
Li-Huei Tsai / Rebecca Pinals
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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ELECTRONIC DEVICE WHICH CAN BE ADHERED TO SKIN AND METHOD FOR MANUFACTURING THE SAME

Technology / Case number: #21220J
Jeehwan Kim / Hanwool Yeun / Eunjoo Kim / Jiyeon Han
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Ultra-High Resolution Mapping of 3D Genome Structure using Region Capture Micro-C

Technology / Case number: #24967
Anders Sejr Hansen / Viraat Goel / Miles Huseyin
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Optimized Alum-Anchored HIV Env Immunogens

Technology / Case number: #24972HJ
Kristen Rodrigues / Christopher Cottrell / Jon Steichen / William Schief / Darrell Irvine
Technology Areas: Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Lipids and Formulations for Intramuscular, In Vitro, and Ex Vivo Transfection of mRNA

Technology / Case number: #23969J
Arnab Rudra / Akash Gupta / Kaelan Reed / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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A Diagnostic and Treatment Prediction Toolkit for Bipolar Disorder based on Polymorphisms in CPG2 Regulatory Domains

Technology / Case number: #23591P
Baovi Vo / Elly Nedivi
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Task Specific Ionic Liquid-Impregnated Polymeric Surface Coatings for Antibacterial, Antifouling and Metal Scavenging Activity

Technology / Case number: #19124
Trevor Hatton / Paul Brown / Sahag Voskian / Cesar De la Fuente Nunez / Ryan Shaw
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Environmental Engineering
Impact Areas: Healthy Living, Advanced Materials
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A Soft Waterproof Omnidirectional Tactile Feedback Sensing Sheet

Technology / Case number: #21524
Tyler Okamoto / Kamal Youcef-Toumi / Jiyoung Chang
Technology Areas: Biomaterials & Bioelectronics / Industrial Engineering & Automation
Impact Areas: Healthy Living, Advanced Materials
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Fluorescence-based detection of protein aggregation and fiber optic-based benchtop instrument

Technology / Case number: #21556
Michael Strano / Daichi Kozawa / Xun Gong / Daniel Salem / Sooyeon Cho / Freddy Nguyen
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Antiviral Compositions and Related Methods

Technology / Case number: #22840
Trevor Hatton / Lev Bromberg
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials
Impact Areas: Healthy Living
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Dielectric Films for the Control of Cell Adhesion

Technology / Case number: #23881
Victor Leon / Baptiste Blanc / Sophia Sonnert / Kripa Varanasi
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Advanced Materials
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Thermal Imaging-based State Estimation of a Stefan Problem with Application to Cell Thawing

Technology / Case number: #24616
Allan Myerson / Richard Braatz / Qihang Zhang / Moo Sun Hong / Ajinkya Vikram Pandit / Prakitr Srisuma / George Barbastathis
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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