A Fully Implantable, Autonomous Closed-Loop System Capable of Long-Term Vital Signs Monitoring and Performing Lifesaving Treatment

A device configured to be implanted in a subject includes a sensing module, a therapeutic module, and a battery. The sensing module includes at least two of an accelerometer, an electrocardiogram (ECG) sensor, a photoplethysmogram (PPG) sensor, and a temperature sensor. The therapeutic module includes a drug reservoir and a reciprocating pump. The battery powers the sensing module and the therapeutic module. The sensing module is configured to detect a biological event in the subject and, upon detection of the biological event, send a signal to the therapeutic module. The therapeutic module is configured to receive the signal from the sensing module and, upon receiving the signal, administer a drug to the subject from the drug reservoir via the pump.

Researchers

Anantha Chandrakasan / Ian Ballinger / Tom Kerssemakers / Peter Chai / Saurav Maji / SeungHo Lee / Hen Wei Huang / Giovanni Traverso

Departments: Dept of Electrical Engineering & Computer Science, Mechanical Engineering, David H Koch Institute for Integrative Cancer Res, Department of Mechanical Engineering
Technology Areas: Biomaterials & Bioelectronics: Health Monitoring / Biotechnology: Biomedical Devices & Systems, Sensors & Monitoring / Computer Science: Bioinformatics / Energy & Distribution: Electrochemical Devices

  • an implantable closed-loop system for monitoring and treatment
    United States of America | Published application

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