A Generalizable, High-Throughput Method to Rapidly add Chemical Moieties to a Small Molecule Library

This innovative technology encompasses a range of organic compounds with diverse applications, including target identification, drug discovery, chemical library production, high-throughput screening, fluorophore and chemiluminescent compound conjugation, and the development of proximity-induced modulators and chimeric molecules. These compounds are designed to contain specific features such as small molecule moieties for target identification, isocyanate and photoactivatable groups, chemical moieties for detecting target-small molecule interactions, proximity-induced modulator elements, as well as fluorophores and chemiluminescent groups, making them versatile tools for various research and drug development endeavors.