Biodegradable Polymers for Messenger RNA Delivery to the Lung
Invention type: Technology
/
Case number: #19314
Provided herein are branched poly(beta-amino esters) (PBAE) useful as vehicles for the delivery of therapeutic agents, such as nucleic acids. The disclosed polymers form stable compositions, and are suitable for the delivery of therapeutic agents via nebulization. Compositions of the disclosed polymers are capable of delivering therapeutic agents such as mRNA to lung epithelial cells.
Researchers
Daniel Anderson
/
Asha Patel
/
James Kaczmarek
/
Kevin Kauffman
Departments: Department of Chemical Engineering
Technology Areas: Biotechnology: DNA & RNA Editing / Chemicals & Materials: Polymers / Drug Discovery and Research Tools: Genomics & Proteomics / Therapeutics: Nucleic Acids
Impact Areas: Healthy Living
-
poly (beta-amino esters) and uses thereof
United States of America | Granted | 11,696,953 -
poly (beta-amino esters) and uses thereof
United States of America | Granted | 11,464,860 -
poly (beta-amino esters) and uses thereof
United States of America | Pending
License this technology
Interested in this technology? Connect with our experienced licensing team to initiate the process.
Sign up for technology updates
Sign up now to receive the latest updates on cutting-edge technologies and innovations.