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Hydrodynamically Controlled Electric Fields for High Throughput Transformation & High Throughput Parallel Transformation Platform

Exclusively Licensed Technology / Case number: #18784
Cullen R. Buie / Rameech McCormack / Paulo Garcia Dominguez / Zhifei Ge
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Industrial Engineering & Automation
Impact Areas: Healthy Living, Sustainable Future

Novel Memory-like NK Cell Based Chimeric Antigen Receptor (CAR) Targeting Mutated NPM1 in Myeloid Malignancies

Exclusively Licensed Technology / Case number: #22960J
Jianzhu Chen / James Ham / Han Dong / Jerome Ritz / Rizwan Romee / Guozhu Xie
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Method for Diagnosing Allergic Reactions

Exclusively Licensed Technology / Case number: #13528
J. Christopher Love / Vinay Tripuraneni / Qing Han
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living

Enhanced Polypeptide Synthesis by UV Monitoring and Feedback Control

Exclusively Licensed Technology / Case number: #18199
Bradley L. Pentelute / Surin Mong / Alexander Mijalis / Dale Thomas / Mark Simon
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Healthy Living

Composition of an Array of Microwells with an Integrated Microfluidic System

Exclusively Licensed Technology / Case number: #13627
J. Christopher Love / Eliseo Papa / Craig Story
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living

Single-Site-Specific Cysteine Arylation Directed by A Genetically Encodable Pi-Clamp

Exclusively Licensed Technology / Case number: #16898
Bradley L. Pentelute / Peng Dai / Chi Zhang
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living

Combined Inhibition of Polo-like kinase 1 (Plk1) and Microtubule Polymerization for the Treatment of Cancer

Exclusively Licensed Technology / Case number: #21961
Michael Yaffe / Jesse C Patterson / Brian A Joughin
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

METHODS FOR IDENTIFYING CHIMERIC ANTIGEN RECEPTOR-TARGETING LIGANDS AND USES THEREOF

Exclusively Licensed Technology / Case number: #22227H
Darrell J Irvine / Benjamin Cossette / Leyuan Ma / Naveen Mehta / Karl Dane Wittrup
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Gene Editing by Cystolic Intracellular Delivery

Exclusively Licensed Technology / Case number: #17635J
Robert Langer / Alexandra Eyerman / Prashant Mali / Marc Lajoie / Armon Sharei / Klavs F. Jensen
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living

A Network-Based Approach to Analyze and Integrate Untargeted Metabolomics with Various High-Throughput Experimental Data

Exclusively Licensed Technology / Case number: #17394
Ernest Fraenkel / Leila Pirhaji
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living

Circulating Tumor Cell Isolation by Size Selective Tagging in a Microfluidic Device

Exclusively Licensed Technology / Case number: #16239
Robert Langer / Nahyun Cho / Viktor Adalsteinsson / Armon Sharei / J. Christopher Love / Klavs F. Jensen
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living

Probing and Manipulating Cell Functions Through Intracellular Delivery

Exclusively Licensed Technology / Case number: #17162HJ
Robert Langer / Sophia Liu / Megan Heimann / George Hartoularos / Shirley Mao / Gregory Szeto / Armon Sharei / Ulrich Von Andrian / Pamela Basto / Siddharth Jhunjhunwala / Darrell J Irvine / Klavs F. Jensen
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

High-Throughput Platform for In-Vivo Sub-Cellular Screens on Vertebrate Larvae

Exclusively Licensed Technology / Case number: #14114
Mehmet Yanik / Cody Gilleland / Carlos Pardo Martin / Tsung-Yao Chang / Steven Charles Wasserman
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living

Stochastic Barcoding Method for Single-Cell Tracking

Exclusively Licensed Technology / Case number: #16514H
Darrell J Irvine / Marc Castellarnau / Gregory Szeto / J. Christopher Love / Joel Voldman
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living

Novel Classes of Channelrhodopsin

Exclusively Licensed Technology, Tangible Property / Case number: #15253TQJE
Gane Wong / Yongku Cho / Nathan Klapoetke / Edward Stuart Boyden / Brian Chow
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living

Rapid Solid Phase Peptide Synthesizer

Exclusively Licensed Technology / Case number: #15911
Klavs F. Jensen / Mark Simon / Bradley L. Pentelute / Patrick Heider / Andrea Adamo
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

SYSTEMS, METHODS, AND APPARATUS FOR IN VITRO SINGLE-CELL IDENTIFICATION AND RECOVERY

Exclusively Licensed Technology / Case number: #17274
J. Christopher Love / Alan Stockdale / Denis Loginov / Viktor Adalsteinsson / Todd Gierahn
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living

A Microfluidic Assay for Rapid Optimization of Bacterial Electroporation

Exclusively Licensed Technology / Case number: #17061
Cullen R. Buie / Jeffrey Moran / Paulo Garcia Dominguez / Zhifei Ge
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living

Method for Assessing Cytotoxicity of Single Cells

Exclusively Licensed Technology / Case number: #13546JQ
J. Christopher Love / Bruce Walker / Boris Julg / Navin Varadarajan
Technology Areas: Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living

Intestines-On-a-Chip for Formulation Screening

Exclusively Licensed Technology / Case number: #17951QJ
Robert Langer / Sarah Saxton / Daniel Minahan / Thomas Von Erlach / Giovanni Traverso
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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