Circulating Tumor Cell Isolation by Size Selective Tagging in a Microfluidic Device
Exclusively Licensed
Invention type: Technology
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Case number: #16239
Isolating or identifying a cell based on a physical property of said cell can include providing a cell suspension; passing said suspension through a microfluidic channel that includes a constriction; passing the cell suspension through the constriction; and, contacting said cell suspension solution with a compound. The constriction can be sized to preferentially deform a relatively larger cell compared to a relatively smaller cell.
Researchers
Robert Langer
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Nahyun Cho
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Viktor Adalsteinsson
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Armon Sharei
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J. Christopher Love
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Klavs F. Jensen
Departments: Office of the Institute Professors, Department of Chemical Engineering
Technology Areas: Biotechnology: Biomedical Devices & Systems, Cell Separation, Synthetic Biology / Diagnostics: Assays / Drug Discovery and Research Tools: Cell Interrogation / Sensing & Imaging: Chemical & Radiation Sensing, Optical Sensing
Impact Areas: Healthy Living
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selective delivery of material to cells
Italy | Granted | 3,033,184 -
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China | Granted | 105,848,793 -
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European Patent Convention | Granted | 3,033,184 -
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Israel | Granted | 244,113 -
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Japan | Granted | 6,502,940 -
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Mexico | Granted | 382,654 -
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Korea (south) | Granted | 10 -
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United States of America | Granted | 10,870,112 -
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Korea (south) | Granted | 10 -
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United States of America | Granted | 11,806,714 -
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Belgium | Granted | 3,033,184 -
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Switzerland | Granted | 3,033,184 -
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Germany | Granted | 3,033,184 -
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Spain | Granted | 3,033,184 -
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France | Granted | 3,033,184 -
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United Kingdom | Granted | 3,033,184 -
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Ireland | Granted | 3,033,184 -
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Netherlands | Granted | 3,033,184 -
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Korea (south) | Granted | 10 -
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Korea (south) | Granted | 10 -
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Singapore | Pending -
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Liechtenstein | Granted | 3,033,184
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