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Methods for the Treatment of Trinucleotide Repeat Expansion Disorders Associated with FAN1 activity via Targeting of FAN1 Splice Site Inhibitory Sequences

Technology / Case number: #24829
Christopher Ng / David Housman
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods for Improving Cross-Ancestry Transferability in Predicting Polygenic Phenotypes from Genetic Variation

Technology / Case number: #24858
Manolis Kellis / Yosuke Tanigawa
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Bioelectronic Devices to Support Transplanted Cells in Vivo for Encapsulated Cell Therapies

Technology / Case number: #23269J
Suman Bose / Robert Langer / Siddharth Krishnan / Matthew Bochenek / Nima Khatib / Daniel Anderson
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living
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Multisensory Gamma Stimulation Promotes Glymphatic Clearance of Amyloid

Technology / Case number: #25696PH
Li-Huei Tsai / Edward Boyden / Ping-Chieh Pao / Cheng-Yi Yang / Mitchell Murdock
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Methods and Apparatuses for Enhancing Scintillation with Optical Nanostructures for Scintillators, LEDs, and Laser Sources

Technology / Case number: #23183J
Steven Kooi / Justin Beroz / Ido Efraim Kaminer / Nicholas Rivera / Yi Yang / Charles Roques-Carmes / Ali Ghorashi / Zin Lin / Nicolas Romeo / John Joannopoulos / Steven Johnson / Marin Soljacic
Technology Areas: Chemicals & Materials / Electronics & Photonics / Sensing & Imaging
Impact Areas: Connected World
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Methods and Apparatus to Generate Terahertz Waves through Cascaded Nonlinear Processes

Technology / Case number: #23257
Charles Roques-Carmes / Yannick Salamin / Zin Lin / Steven Johnson / Marin Soljacic
Technology Areas: Electronics & Photonics / Energy & Distribution / Sensing & Imaging
Impact Areas: Sustainable Future
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New Add-on Device for In Situ Laser Shot Peening during Selective Laser Melting

Technology / Case number: #23130
Cemal Tasan / Jiyun Kang
Technology Areas: Electronics & Photonics / Industrial Engineering & Automation
Impact Areas: Connected World
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DC-DC Converter Based on Piezoelectric Transformer

Technology / Case number: #23548
Jessica Boles / Elaine Ng / David Perreault / Jeffrey Lang
Technology Areas: Electronics & Photonics / Energy & Distribution / Sensing & Imaging
Impact Areas: Sustainable Future
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Parallel Microcavity Trimming by Structured-Laser Illumination

Technology / Case number: #24317
Dirk Englund / Christopher Panuski / Ian Christen
Technology Areas: Chemicals & Materials / Electronics & Photonics
Impact Areas: Advanced Materials
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Methods of Enhancing the Stability of Quantum Noise Limited Feedback Oscillators

Technology / Case number: #24689
Vivishek Sudhir / Hudson Loughlin
Technology Areas: Electronics & Photonics
Impact Areas: Advanced Materials
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Freely Scalable Quantum Computing using a 2D Atomic Emitter Array with Massively Parallel Optical Interconnects

Technology / Case number: #21670
Dirk Englund / Hyeongrak Choi
Technology Areas: Computer Science / Electronics & Photonics / Sensing & Imaging
Impact Areas: Uncharted Frontiers, Advanced Materials
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Using CRISPR/Cas9 to Encode Cellular History

Technology / Case number: #18025R
Alexander Shalek / Alethe Gaillard de Saint Germain
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Genotype-Directed Local Delivery of Targeted Therapeutics at the Tumor Margin

Technology / Case number: #19863J
Carlo Giovanni Traverso / Ameya Kirtane / Daniel Cahill / Ganesh Shankar / Robert Langer
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Formulated, Biodegradable Polymeric Nanoparticles for Nucleic Acid Delivery to Non-Liver Targets

Technology / Case number: #19802
Kevin Kauffman / James Kaczmarek / Asha Patel / Luke Rhym / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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High-Throughput Screens for Exploring Biological Functions of Microscale Biological Systems

Technology / Case number: #19737JR
Paul Blainey / Navpreet Ranu
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Using over Wnt ing to Treat Colon Cancer: Small Molecule GSK3 Inhibitors and Novel Protein Isolation

Technology / Case number: #23378J
George Eng / Omer Yilmaz / Jonathan Braverman
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Single-Cell RNA Sequencing Using Click-Chemistry

Technology / Case number: #20396
Dig Mahat / Phillip Sharp
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Diagnosis of Malignancy Using Developmental Relationships and Machine Learning

Technology / Case number: #23356
Salil Garg / Enrico Moiso
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Bioinspired Design of Self-Adjuvanted C3d-Fusion SARS-CoV-2 mRNA Vaccines

Technology / Case number: #23326
Robert Langer / Bowen Li / Allen Jiang / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Ingestible Chemical Energy Harvesting System with Extended Lifetime

Technology / Case number: #23174
Carlo Giovanni Traverso / Jason Li / So-Yoon Yang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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