Genotype-Directed Local Delivery of Targeted Therapeutics at the Tumor Margin

Provided herein are pharmaceutical compositions for local administration of metabolic inhibitors, methods of locally administering such compositions, and rapid diagnostic methods for identifying mutant allele during the course of a surgical procedure.

Researchers

Carlo Giovanni Traverso / Ameya Kirtane / Daniel Cahill / Ganesh Shankar / Robert Langer

Departments: Department of Mechanical Engineering, David H Koch Institute for Integrative Cancer Res, Office of the Institute Professors
Technology Areas: Biotechnology: Biomedical Devices & Systems / Chemicals & Materials: Polymers / Drug Discovery and Research Tools: Genomics & Proteomics / Therapeutics: Small Molecules
Impact Areas: Healthy Living

  • genotype-directed local delivery of targeted therapeutics
    United States of America | Published application

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