Formulated, Biodegradable Polymeric Nanoparticles for Nucleic Acid Delivery to Non-Liver Targets
Invention type: Technology
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Case number: #19802
The present disclosure relates to improvements in the selection and formulation of PBAE polymers using a design of experiment approach, in which statistical methods are used to limit possible experimental conditions. The present disclosure relates to improved PBAE polymers and formulations.
Researchers
Kevin Kauffman
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James Kaczmarek
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Asha Patel
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Luke Rhym
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Daniel Anderson
Departments: Department of Chemical Engineering
Technology Areas: Biotechnology: DNA & RNA Editing / Chemicals & Materials: Polymers / Drug Discovery and Research Tools: Genomics & Proteomics / Therapeutics: Small Molecules
Impact Areas: Healthy Living
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polymer-lipids and compositions
United States of America | Granted | 11,608,412
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