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In Vitro and in Vivo Delivery of Complex Genetic Circuits up to 33kb Using Engineered HSV-1

Technology / Case number: #20746
Ron Weiss / Ross Jones / Jin Huh / Maria Hottelet Foley
Technology Areas: Diagnostics / Drug Delivery
Impact Areas: Healthy Living
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Phosphorylation-Based miRNA High Sensor

Technology / Case number: #19683
Ron Weiss / Ross Jones / Jin Huh
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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A Signal Inverter Module for RNA Cleavers: Detecting and Evaluating miRNA, Ribozymes, and Ribonucleases

Technology / Case number: #19604
Ron Weiss / Breanna DiAndreth
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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New Genetic Circuit Topologies for High Performance Multi-Input MicroRNA Sensors for Classifying Living Cell State

Technology / Case number: #19534
Ron Weiss / Jin Huh
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Methods to Spatially Profile Protease Activity in Tissue and Sections

Technology / Case number: #19415H
Sangeeta Bhatia / Ester Kwon / Jaideep Dudani / Andrew Warren
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Optimized Opsin Trafficking with Fluorescence-Dead Protein Fusions

Technology / Case number: #18783TE
Edward Stuart Boyden / Demian Park / Aimei Yang / Kiryl Piatkevich
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Computational Reconfigurable Imaging Spectrometer (CRISP)

Technology / Case number: #19426L
Sumanth Kaushik / Ryan Sullenberger / Adam Milstein / Yaron Rachlin / Charles Wynn
Technology Areas: Agriculture & Food / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living, Sustainable Future
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Methods to Specifically Profile Protease Activity at Lymph Nodes

Technology / Case number: #18619H
Sangeeta Bhatia / Naveen Mehta / Jaideep Dudani / Andrew Warren / Karl Dane Wittrup / Darrell J Irvine
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Novel Method to Correct Altered Synaptic Signaling in Autism and Intellectual Disability

Technology / Case number: #18383PHJ
Mark Bear / Robert Lefkowitz / Laura Stoppel / Benjamin Auerbach
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Methods and Uses for Remotely Triggered Protease Activity Measurements

Technology / Case number: #18272H
Sangeeta Bhatia / Simone Schuerle-Finke / Jaideep Dudani / Piyush Jain / Gabriel Kwong
Technology Areas: Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Oligomeric Conjugates for siRNA Delivery and Glucose-Responsive Insulins

Technology / Case number: #15977J
Robert Langer / Rosemary Kanasty / Arturo Vegas / Daniel Anderson
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Peristaltic Pumps for Vacuum Generation

Technology / Case number: #24513J
Luis Fernando Velasquez-Garcia / Pam Randhawa / Hanjoo Lee
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Highly Sensitive and Multiplexed Detection of Analytes with Mass Reporters and Quantitative Mass Spectrometry

Technology / Case number: #14585H
Sangeeta Bhatia / Gabriel Kwong
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
License

Method to Pattern Cells (Crude Blood) on a (Planar) Surface

Technology / Case number: #15262
Shivang Dave / German Serrano
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Seismic Cloaking Structure Design to Protect High Value Assets from Hazardous Earthquakes

Technology / Case number: #18225L
Mordechai Rothschild / Charles Doll / Robert Haupt / Shaun Berry / Vladimir Liberman
Technology Areas: Energy & Distribution
Impact Areas: Healthy Living
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Retroreflectors for Remote Detection

Technology / Case number: #14617L
Mordechai Rothschild / Michael Switkes
Technology Areas: Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Modular System for Lyophilization

Technology / Case number: #22603
Alexander Slocum / Bernhardt Trout
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living
License

Layer-by-Layer Based Nanoparticles for Systemic Delivery Applications

Technology / Case number: #14680
Paula Hammond / Zhiyong Poon
Technology Areas: Chemicals & Materials / Computer Science / Drug Delivery
Impact Areas: Healthy Living
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Bioprocess and Microbe Engineering for Total Carbon Utilization in Biofuel Production

Technology / Case number: #14119
Gregory Stephanopoulos
Technology Areas: Environmental Engineering
Impact Areas: Climate Stabilization
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High-throughput Cellulose based Pulldown Assay

Technology / Case number: #23189DEJ
Peter Preiser / Sing Mei Lim / Hoi Lok Cheng / Say Yong Ng / Megan McBee / Huan Jia / Patthara Kongsuphol / Hadley Sikes
Technology Areas: Diagnostics
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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