Ingestible Physiological Status Monitoring (PSM) Device (the "PSM Pill")


This invention provides real-time internal monitoring of vital signs with improved accuracy over external measurements, useful for field assessment of patients or home monitoring and management of chronic illnesses. This device may also be used for operational safety monitoring for military personnel or first responders, or to improve performance and safety for athletes. This device can detect a number of medical conditions including, sepsis, arrhythmias, aortic stenosis, hypertrophy, asthma and chronic obstructive pulmonary disease (COPD) exacerbations. 

Problem Addressed

Physiological status monitoring (PSM) systems can provide data for necessary preventative interventions, improved performance, risk mitigation, or monitoring of illness or after injury. Current PSM devices are less than ideal due to a number of limitations including limited battery life, poor signal fidelity, and general ergonomic obtrusiveness. This invention is an ingestible, minimally intrusive PSM device that measures heart rate, breathing rate, and core temperature for reliable and rapid monitoring of physiological status. 


This small ingestible PSM device enters the digestive tract as a pill and contains a thermistor to measure temperature and an electret hydrophone and processing circuitry to collect, amplify, and filter audio signals to derive heart and breathing rates from noisy data. The data is wirelessly transmitted to a receiver outside the patient. This device can collect data anywhere along the digestive tract regardless of contact with tissue. The PSM device can be either transient and excreted normally, or persistent and affixed in the digestive tract. The PSM device has a relatively long battery life of at least 4 days, but persistent devices may be powered through inductively coupled or wireless resonant recharging. 


  • Inexpensive 
  • Extended battery life with optional recharging capabilities
  • Operational anywhere in the GI tract and can be transient or persistent
  • Improved patient comfort
  • Measures true core temperature which isn’t currently obtainable except with rectal